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Linked and Unlinked Genes

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Estimated time: 4 minutes
CISCE: Class 12

Definition: Linked genes

Genes located on the same chromosome and that tend to be inherited together as a unit are called linked genes.

CISCE: Class 12

Definition: Unlinked genes

Genes located on different chromosomes that assort independently during meiosis are called unlinked genes.

CISCE: Class 12

Key Points: Linked and Unlinked Genes

  • Linked genes are located on the same chromosome and collectively form a specific linkage group.
  • The total number of linkage groups in an organism is exactly equal to its haploid chromosome number (for example, 23 in humans and 4 in Drosophila).
  • Unlinked genes are situated on different chromosomes and undergo independent assortment, consistently producing a classic 9:3:3:1 F2 phenotypic ratio and a 1:1:1:1 test cross ratio.
  • Linked genes do not follow independent assortment; Mendel never observed linkage because the seven specific traits he studied were unlinked and assorted independently.
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