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Hormonal Control of Menstrual Cycle

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CISCE: Class 12

Key Points: Hormonal Control of the Menstrual Cycle

  • The menstrual cycle is regulated mainly by five hormones: GnRH, FSH, LH, estrogen, and progesterone, acting in a coordinated manner.
  • GnRH released from the hypothalamus stimulates the anterior pituitary to secrete FSH and LH.
  • FSH promotes growth of ovarian follicles and estrogen secretion, while estrogen repairs and thickens the uterine endometrium.
  • A mid-cycle surge of LH induces ovulation and converts the ruptured follicle into the corpus luteum, which secretes progesterone.
  • Progesterone maintains the endometrium for implantation; if fertilization does not occur, hormone levels fall, leading to menstruation and initiation of a new cycle.
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