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Tamil Nadu Board of Secondary EducationHSC Science Class 12

Infertility

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Estimated time: 13 minutes
CBSE: Class 12
Maharashtra State Board: Class 12
CISCE: Class 12

Introduction

Infertility is the inability of a couple to produce children despite unprotected sexual cohabitation.

A couple is considered infertile if they are unable to conceive after approximately 12 months to 2 years of regular, unprotected sexual intercourse.

Types of Infertility:

Type Meaning
Primary Infertility When a couple has never been able to achieve pregnancy​
Secondary Infertility When a couple is unable to conceive after at least one prior successful pregnancy​
CBSE: Class 12
Maharashtra State Board: Class 12
CISCE: Class 12

Causes of Infertility

Infertility may be caused by physical, congenital, diseases, drugs, immunological, or even psychological factors.​

 
Category Causes in Males Causes in Females
Hormonal Low LH, FSH, androgen, prolactin; thyroid disorder; pituitary dysfunction​ PCOS (Polycystic Ovarian Syndrome); hormonal imbalance; pituitary/hypothalamic disorders
Structural / Anatomical Varicocele (enlarged scrotal veins); undescended testes (cryptorchidism); blocked vas deferens or ejaculatory ducts Blocked fallopian tubes; uterine fibroids/polyps; endometriosis; septate uterus
Sperm / Gamete Quality Oligospermia (low sperm count); azoospermia (no sperm); poor motility; abnormal morphology Poor egg quality; primary ovarian insufficiency; premature ovarian failure
Infections / Disease STIs (gonorrhoea, chlamydia); mumps; prostate infections; seminal vesicle infections Pelvic Inflammatory Disease (PID); STIs causing tubal damage; endometriosis
Immunological Antisperm antibodies (produced by both men and women)​ Hostile cervical mucus; immune rejection of sperm or embryo​
Lifestyle / Environmental Smoking; excessive alcohol; anabolic steroid use; high heat exposure (tight clothing, laptops, saunas) Obesity/underweight; eating disorders; over-exercising; chemotherapy/radiation
Psychological Stress-induced erectile dysfunction; anejaculation​ Stress-induced anovulation​
Congenital / Genetic Klinefelter syndrome; cystic fibrosis; chromosomal disorders​ MRKH syndrome; chromosomal disorders; sickle cell anaemia
CBSE: Class 12
Maharashtra State Board: Class 12
CISCE: Class 12

Diagnosis

CBSE: Class 12
Maharashtra State Board: Class 12
CISCE: Class 12

Treatment

  • Hormonal therapy: Testosterone injections for males; gonadotropin injections to stimulate ovulation in females
  • Surgery: Varicocele repair; tubal re-canalisation; removal of fibroids or endometriotic tissue​
  • Lifestyle modifications: Weight management; stopping smoking/alcohol; avoiding excessive heat
  • Counselling: For psychological causes
CBSE: Class 12
Maharashtra State Board: Class 12
CISCE: Class 12

Key Points: Infertility

  • Infertility is the inability to conceive after 12 months or more of regular unprotected intercourse and may be due to male, female, or both partners.
  • Male infertility includes low sperm count, no sperm production, poor sperm motility, or abnormal sperm structure.
  • Female infertility may result from hormonal imbalance, poor egg production, or defects in reproductive organs like the ovaries, fallopian tubes, uterus, or cervix.
  • Mechanical or physiological problems, such as blocked reproductive tracts or thick cervical mucus, can prevent fertilisation.
  • Infertility is diagnosed and treated by identifying the cause and using methods like hormonal therapy, surgery, or lifestyle changes.
  • Assisted Reproductive Technologies (ART) help infertile couples and include IVF, ICSI, GIFT, ZIFT, AI, and IUI, which assist in fertilisation and conception.

Shaalaa.com | Infertility: Artificial Insemination

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