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Difference Between Polygenic Inheritance and Pleiotropy

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Estimated time: 3 minutes
CBSE: Class 12

Key Points: Difference Between Polygenic Inheritance and Pleiotropy

Aspect Polygenic Inheritance Pleiotropy
Focus of study Traits with distinct alternate forms (e.g., flower colour) Single gene influencing multiple phenotypic traits
Trait definition Sharply defined, such as purple or white flower colour Spread across a spectrum, like human height
Genetic control Controlled by three or more genes Controlled by a single gene
Variation Continuous variation Diverse phenotypic expressions
Influencing factors Influenced by genetic factors and the environment Often due to a gene’s effect on metabolic pathways
Example Human skin colour Phenylketonuria (PKU) disease
Mechanism of action Additive effect of alleles on phenotype Gene’s impact on various metabolic pathways
Phenotypic effects Determined by a combination of alleles in the genotype Multiple phenotypic effects from a single gene mutation
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