हिंदी

Mechanism of Respiration > Internal Respiration

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Estimated time: 5 minutes
CBSE: Class 12
Maharashtra State Board: Class 12

Key Points: Mechanism of Respiration > Inspiration

  • Meaning - O₂ from blood is delivered to cells/tissues, and CO₂ from cells passes into the blood.
  • O₂ Transport - 97% as oxyhaemoglobin (HbO₂) via RBCs, 3% dissolved in plasma. One Hb molecule has 4 Fe²⁺ ions, each binding one O₂: Hb + 4O₂ → Hb(O₂)₄
  • Bohr Effect - Rise in CO₂ / lower pH / higher temperature → reduces Hb-O₂ affinity (curve shifts right) → O₂ released to tissues.
  • Haldane Effect - Binding of O₂ with Hb displaces CO₂ from blood (curve shifts left, higher Hb-O₂ affinity).
  • CO₂ Transport - 70% as bicarbonate ions (HCO₃⁻) in plasma | 23% as carbaminohaemoglobin | 7% dissolved in plasma.
  • Chloride Shift (Hamburger's Phenomenon) - When CO₂ enters blood, Cl⁻ moves into RBCs (Na⁺ stays behind). When CO₂ leaves, Cl⁻ moves back out. This alternate Cl⁻ movement maintains electrical balance.

Shaalaa.com | Breathing and Exchange of Gases part 13 (Transport of oxygen gas)

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Breathing and Exchange of Gases part 13 (Transport of oxygen gas) [00:12:09]
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