हिंदी

Formation of Antigen-Antibody Complex

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Estimated time: 3 minutes
Maharashtra State Board: Class 12

Key Points: Formation of Antigen-Antibody Complex

  • Serology: The study of antigen-antibody interactions is called serology.
  • Key Terms: Combining sites on antigen = Epitopes; binding sites on antibody = Paratopes (on variable region).
  • Lock & Key Mechanism: Epitopes bind paratopes in a lock and key manner to form the antigen-antibody complex. Small variations in the variable region make each antibody highly specific.
  • Antigen on Blood Cells: RBCs carry several antigens giving rise to different blood groups — ABO, Rh, Duffy, Kidd, MNS, Bombay, etc. (genetically determined).
  • Specificity: Each antibody binds only to its specific antigen, imparting individuality to all humans.
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