Operon Concept

Topics

Reproduction in Lower and Higher Plants
Reproduction in Lower and Higher Animals
Inheritance and Variation
- Heredity
- Gregor Johann Mendel – Father of Genetics
- Mendel's Experiments on Inheritance
- Reasons for Mendel's Success
- Genetic Terminology
- Monohybrid Cross
- Dihybrid Cross
- Mendel's Laws > The Law of Dominance
- Mendel's Laws > The Law of Segregation (Law of Purity of Gametes)
- Mendel's Laws > The Law of Independent Assortment
- Back Cross and Test Cross
- Deviations from Mendel’s Findings
- Exceptions to Mendel's Principles > Incomplete Dominance
- Exceptions to Mendel's Principles > Co-Dominance
- Exceptions to Mendel's Principles > Multiple alleles
- Exceptions to Mendel's Principles > Pleiotropy
- Chromosomal Theory of Inheritance
- Chromosomes - The Carriers of Heredity
- Types of Chromosomes
- Linkage and Crossing Over
- Autosomal Inheritance
- Sex Linked Inheritance
- Colour blindness
- Haemophilia
- Sex Determination
- Sex Determination in Humans
- Sex Determination in Birds
- Sex Determination in Honey Bees
- Human Genetic Disorders
- Thalassemia
- Down's syndrome (Mongolian Idiocy)
- Turner's Syndrome
- Klinefelter's Syndrome
- Overview of Inheritance and Variation
Molecular Basis of Inheritance
- Deoxyribonucleic Acid (DNA)
- Griffith’s Experiment
- Avery, McCarty and MacLeod’s Experiment
- The Hershey-Chase Experiment
- Packaging of DNA Helix
- DNA Replication
- Mechanism of DNA Replication
- Semi-Conservative Replication
- Protein Synthesis
- Transcription
- Transcription Unit and the Gene
- Genetic Code
- Characterestic of the Genetic Code
- Mutations and Genetic Code
- tRNA – the Adapter Molecule
- Translation
- Mechanism of Translation
- Regulation of Gene Expression
- Operon Concept
- The Lac Operon
- Genomics
- Human Genome Project
- DNA Fingerprinting
- Overview of Molecular Basis of Inheritance
Origin and Evolution of Life
- Origin of Life on Earth
- Redi's and Louis Pasteur’s Experiment
- Chemical Evolution of Life
- Urey and Miller’s Experiment
- The RNA World
- Organic Evolution
- Darwin’s Theory of Natural Selection (Darwinism)
- Basic Postulates of Darwinism
- Drawbacks and Criticism of Darwinism
- Mutation Theory
- Modern Synthetic Theory of Evolution
- Modern Synthetic Theory of Evolution > Genetic Variations
- Modern Synthetic Theory of Evolution > Natural Selection
- Modern Synthetic Theory of Evolution > Isolation
- Mechanism of Organic Evolution
- Hardy Weinberg’s Principle
- Adaptive Radiation
- Evidences of Organic Evolution
- Evidences of organic evolution > Palaeontology
- Connecting Links
- Homology and Homologous Organs
- Analogy and Analogous Organs
- Vestigial Organs
- Molecular (Genetic) Evidences
- Speciation
- Geological Time Scale
- Human Evolution
- Stages of Human Evolution
- Overview of Origin and Evolution of Life
Plant Water Relation
- Properties of Water
- Water Absorbing Organ
- Water Available to Roots for Absorption
- Diffusion
- Osmosis
- Imbibition
- Osmotic Pressure
- Water Potential (ψ)
- Turgidity and Flaccidity (Plasmolysis)
- Path of Water Across the Root
- Mechanism of Absorption of Water
- Translocation of Water
- Root Pressure Theory (Vital Theory)
- Capillarity Theory (physical force theory)
- Cohesion-Tension Theory (Transpiration pull theory)
- Transport of Mineral Ions
- Transportation of Food and Other Substances
- Concept of Transpiration
- Types of Transpiration > Cuticular Transpiration
- Types of Transpiration > Lenticular Transpiration
- Types of Transpiration > Stomatal Transpiration
- Structure of Stomatal Apparatus
- Significance of Transpiration
- Overview of Plant Water Relation
Plant Growth and Mineral Nutrition
Respiration and Circulation
Control and Co-ordination
Human Health and Diseases
Enhancement of Food Production
Human Reproduction
Biotechnology
Organisms and Populations
Ecosystems and Energy Flow
Biodiversity, Conservation and Environmental Issues
- Biodiversity
- Levels of Biodiversity
- Patterns of Biodiversity
- Importance of Species Diversity to the Ecosystem
- Biodiversity Current Scenario
- Loss of Biodiversity
- Threatened Species
- Conservation of Biodiversity
- Biodiversity Conservation Methods
- Biological Diversity Act, 2002
- Environmental Issues
- Air Pollution
- Effects of Air Pollution
- Major Air Pollutants
- Prevention and Control of Air Pollution
- Noise Pollution
- Water Pollution
- Sources of Water Pollution
- Prevention and Control of Water Pollution
- Solid Waste Management
- Greenhouse Effect
- Global Warming
- Ozone Layer Depletion
- Deforestation and Its Causes
- Mission Harit Maharashtra
- Overview of Biodiversity, Conservation and Environmental Issues

Estimated time: 5 minutes

Maharashtra State Board: Class 12

Key Points: Operon Concept

The operon model was given by F. Jacob & J. Monod (1961). It controls gene expression in prokaryotes and is based on the lac operon in E. coli.
An operon has 4 parts — Regulator (makes repressor), Promoter (RNA Polymerase binds here), Operator (controls structural genes), and Structural genes (lac-z, lac-y, lac-a — encode enzymes for lactose digestion).
The inducer is allolactose. It binds to the repressor, inactivates it, and allows transcription to occur.
Without lactose (Operon OFF): Repressor binds to the operator → blocks RNA polymerase → no enzymes produced.
With lactose (Operon ON): Lactose is converted to allolactose → inactivates repressor → operator is free → RNA polymerase transcribes → β-galactosidase, Permease, Transacetylase are produced → lactose broken down into galactose + glucose.
The lac operon is an inducible operon — normally OFF, switched ON only when lactose is present.
Important bonds — Hydrogen bond: links nitrogen bases; Glycosidic bond: base to sugar; Phosphoester bond: phosphate to sugar; Phosphodiester bond: links nucleotides; Peptide bond: links amino acids.

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Topics

Reproduction in Lower and Higher Plants

Reproduction in Lower and Higher Animals

Inheritance and Variation

Molecular Basis of Inheritance

Origin and Evolution of Life

Plant Water Relation

Plant Growth and Mineral Nutrition

Respiration and Circulation

Control and Co-ordination

Human Health and Diseases

Enhancement of Food Production

Human Reproduction

Biotechnology

Organisms and Populations

Ecosystems and Energy Flow

Biodiversity, Conservation and Environmental Issues

Key Points: Operon Concept

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