हिंदी

Coagulation of Blood

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Estimated time: 2 minutes
Maharashtra State Board: Class 12

Key Points: Coagulation of Blood

  • When a blood vessel is injured, platelets disintegrate, and injured tissue releases thromboplastin, which initiates the clotting process.
  • Thromboplastin converts inactive prothrombin → thrombin in the presence of Ca²⁺ ions (via formation of prothrombinase/thrombokinase).
  • Thrombin then converts soluble fibrinogen → insoluble fibrin threads.
  • Fibrin threads trap formed elements (RBCs, WBCs, platelets) to form a dark reddish-brown clot (scum), sealing the wound.
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