मराठी

Structure of Antibody

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Estimated time: 3 minutes
Maharashtra State Board: Class 12

Key Points: Structure of Antibody

  • Nature: Y-shaped glycoproteins called Immunoglobulins (Igs), produced by plasma cells at ~2000 molecules per second.
  • Structure: Made of 4 polypeptide chains — 2 Heavy (H) and 2 Light (L) chains, held by disulphide bonds.
  • Regions: Each chain has a Variable region (antigen-binding site) and a Constant region. The junction between arms and stem is the hinge.
  • Antigen Binding: Variable region (paratope) binds to a specific antigen, forming an antigen-antibody complex. Most antibodies have two binding sites — called bivalent.
  • Types: Five immunoglobulins — IgG, IgM, IgA, IgE, and IgD.
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