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Mechanism of Hormone Action

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Estimated time: 3 minutes
Maharashtra State Board: Class 12

Key Points: Mechanism of Hormone Action

  • Hormones bind to specific receptors in target tissues only, forming a hormone-receptor complex → causes biochemical changes.
  • Two receptor types — Membrane-bound (cell surface) and Intracellular (inside cell/nucleus).
  • Membrane Receptor — Water-soluble hormones bind surface receptor → adenylate cyclase → ATP converts to cAMP (2nd messenger) → enzyme activation. Other 2nd messengers: Ca²⁺, cGMP, IP₃.
  • Intracellular Receptor — Lipid-soluble hormones cross membrane → bind cytoplasm receptor → complex enters nucleus → activates DNA → mRNA → protein synthesis.
  • Membrane receptor = faster, short-lived; Intracellular receptor = slower, long-lasting.

Shaalaa.com | Chemical Coordination and Integration part 17 (Hormones Group, receptors)

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Chemical Coordination and Integration part 17 (Hormones Group, receptors) [00:07:44]
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