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Protein Synthesis - Translation

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Estimated time: 5 minutes
  • Definition: Triplet Codon
  • Definition: Translation
Maharashtra State Board: Class 10

Definition: Triplet Codon

A sequence of three nucleotides on mRNA that codes for a specific amino acid is called a triplet codon.

CBSE: Class 12
Maharashtra State Board: Class 10
CISCE: Class 12

Definition: Translation

The process of protein synthesis in which the message on mRNA is decoded with the help of tRNA to form a specific sequence of amino acids is called translation.

Maharashtra State Board: Class 12

Key Points: Translation

  • Translation is the process in which mRNA codons are read to form a sequence of amino acids, producing a polypeptide (protein) on ribosomes.
  • It requires amino acids, mRNA, tRNA, ribosomes, ATP, Mg²⁺ ions, enzymes, and release factors.
  • Ribosomes are the site of protein synthesis and have three tRNA binding sites: A site, P site, and E site.
  • Initiation begins with the start codon AUG, where the initiator tRNA binds at the P site, and ribosomal subunits join.
  • During elongation, amino acids are added one by one, peptide bonds are formed, and tRNA shifts from A site to P site.
  • Termination occurs when a stop codon (UAA, UAG, UGA) is reached, the release factor binds, and the polypeptide chain is released.
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