हिंदी

Autoimmunity - Immunodeficiency Disorders

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CISCE: Class 12

Key Points: Immunodeficiency Disorder

Immunodeficiency Disorder Type Cells Affected Key Features
Severe Combined Immunodeficiency (SCID) Congenital T-cells and B-cells absent Extremely susceptible to infections; patients may need germ-free isolation
Di George’s Syndrome Congenital T-cells absent Thymus absent or poorly developed; only B-cells present
Agammaglobulinemia Congenital B-cells deficient Recurrent severe infections; T-cell function normal
Acquired Immunodeficiency Syndrome (AIDS) Acquired T-cells severely reduced Fatal disease causing severe cellular immunodeficiency and widespread infections
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