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Pathogens - Barriers to Invasion by Pathogens

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CISCE: Class 12

Key Points: Barriers to Invasion by Pathogens

  • Pathogens cause disease by producing toxins that damage host tissues and weaken host defence cells.
  • The severity of disease depends on the pathogenicity and virulence of the microorganism and the susceptibility of the host.
  • Virulence refers to the ability of a microbial strain to infect, invade tissues and produce toxins, while attenuated strains show reduced virulence.
  • Hosts resist infections through defensive mechanisms influenced by their genetic makeup and environmental conditions.
  • The principle of immunity and vaccination, discovered by Jenner and later developed by Pasteur, protects the host by using attenuated or mild forms of pathogens.
 
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