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Mechanism of Concentration of the Filtrate

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Estimated time: 2 minutes
CBSE: Class 12

Key Points: Mechanism of Concentration of the Filtrate

  • Mammals produce concentrated urine with the help of Henle's loop and vasa recta through a counter current mechanism.
  • Filtrate in Henle's loop and blood in the vasa recta both flow in opposite directions (counter-current).
  • Counter current maintains osmolarity from 300 mOsmol/L (cortex) to 1200 mOsmol/L (inner medulla).
  • The gradient is mainly created by NaCl (transported by the ascending limb) and urea (transported by the collecting tubule).
  • Interstitial gradient allows water to move out of the collecting tubule, concentrating urine up to 4 times more than the initial filtrate.

Shaalaa.com | Excretory Products and Elimination part 12 (Counter current mechanism)

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Excretory Products and Elimination part 12 (Counter current mechanism) [00:19:35]
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