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Question
Write a short note on the following:
Gabriel phthalimide synthesis
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Solution
Gabriel synthesis is used for the preparation of primary amines. Phthalimide, on treatment with ethanolic potassium hydroxide, forms potassium salt of phthalimide, which on heating with alkyl halide followed by alkaline hydrolysis, produces the corresponding primary amine. Aromatic primary amines cannot be prepared by this method because aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.
RELATED QUESTIONS
Classify the following amine as primary, secondary or tertiary:
(C2H5)2NH
In the following
The compound ‘B’ is _______.
(A) Propan–1–amine
(B) Propan–2–amine
(C) Isopropylamine
(D) Dimethylamine
Choose the most correct option.
The hybridisation of nitrogen in primary amine is ____________.
Choose the most correct option.
Carbylamine test is given by ____________.
Choose the most correct option.
Identify ‘B’ in the following reactions
\[\ce{CH3 - C ≡ N ->[Na/C2H5OH] A ->[NaNO2/dilHCl]B}\]
What are amines?
How are amines classified?
Assertion: Acetamide on reaction with KOH and bromine gives acetic acid.
Reason: Bromine catalyses hydrolysis of acetamide.
When aniline reacts with acetic anhydride the product formed is ____________.
Write a short note on the following.
Carbylamine reaction
Account for the following.
pKb of aniline is more than that of methylamine.
Arrange the following:
In increasing order of solubility in water:
C6H5NH2, (C2H5)2NH, C2H5NH2
How will you prepare propan-1-amine from butane nitrile?
How will you prepare propan-1-amine from 1-nitropropane?
Identify A, B and C.
\[\ce{CH3 - NO2 ->[LiAlH4] A ->[2CH3CH2Br] B ->[H2SO4] C}\]
The following amine can be classified as (C2H5)2NH:
Complete the following reaction.
The amine formed from an amide by mean of bromine and alkali has how many number of carbon atoms?
Which among the following is the strongest Bronsted base?
Among the following, which is the strongest base?
Arrange the increasing order of solubility in water.
\[\ce{C2H5Cl, C2H5NH2, C2H5OH}\]
Write a short note on the following.
Ammonolysis
Write short note on Ammonolysis.
Write short note on the following:
Ammonolysis
Write a short note on the following.
Ammonolysis
Write a short note on the following.
Ammonolysis
