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Question
Write a short note on the following.
Schotten-Baumann reaction
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Solution
Aniline reacts with benzoyl chloride (C6H5COCl) in the presence of NaOH to give N-phenyl benzamide. This reaction is known as the Schotten Baumann reaction. The acylation and benzoylation are nucleophilic substitutions.
\[\begin{array}{cc}
\phantom{..........}\ce{O}\phantom{..........................}\ce{O}\phantom{..}\\
\phantom{.........}||\phantom{..........................}||\phantom{.}\\
\ce{\underset{(Aniline)}{C6H5 - NH2} + \underset{(Benzoyl chloride)}{C6H5 - C - Cl} ->[NaOH] \underset{(N-phenyl benzamide)}{C6H5 - NH - C - C6H5} + HCl}
\end{array}\]
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RELATED QUESTIONS
Write the number of moles of ethanoyl chloride required for complete acylation of N, N-dimethylaniline.
Assertion: Acetamide on reaction with KOH and bromine gives acetic acid.
Reason: Bromine catalyses hydrolysis of acetamide.
Which of the following amines does not undergo acetylation?
IUPAC name for the amine is:
\[\begin{array}{cc}
\phantom{.}\ce{CH3}\\
|\phantom{..}\\
\ce{CH3 - N - C - CH2 - CH3}\\
\phantom{.}|\phantom{.....}|\phantom{........}\\
\phantom{}\ce{CH3}\phantom{..}\ce{C2H5}\phantom{....}
\end{array}\]
Account for the following.
Ethylamine is soluble in water whereas aniline is not.
How will you convert diethylamine into N, N-diethyl acetamide?
The main product is formed by treating an alkyl or benzyl halide with excess ammonia ____________.
The amine formed from an amide by mean of bromine and alkali has how many number of carbon atoms?
Write a short note on the following.
Ammonolysis
Write short note on the following:
Ammonolysis
