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Question
Which of the following amines can be prepared by Gabriel synthesis.
(i) Isobutyl amine
(ii) 2-Phenylethylamine
(iii) N-methylbenzylamine
(iv) Aniline
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Solution
(i) Isobutyl amine
(ii) 2-Phenylethylamine
Explanation:
Gabriel synthesis is a method for producing primary amines. When phthalimide is treated with ethanolic potassium hydroxide, it forms a potassium salt of phthalimide, which when heated with an alkyl halide and then alkaline hydrolyzed yields the corresponding primary amine.
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RELATED QUESTIONS
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(i)
(ii)
(iii)
(iv)
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| Column I | Column II | ||
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