Advertisements
Advertisements
Question
State the role of C-peptide in human insulin.
Advertisements
Solution
Mammalian insulin is synthesized as a prohormone, which undergoes processing to become a fully mature and functional insulin molecule. The prohormone contains an extra chain called C-peptide, which is removed during the conversion of prohormone to the mature hormone insulin.
APPEARS IN
RELATED QUESTIONS
Why do children cured by enzyme-replacement therapy adenosine deaminase deficiency need periodic treatment?
Compare and contrast the advantages and disadvantages of the production of genetically modified crops.
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
PCR proceeds in three distinct steps governed by temperature, they are in order of ____________.
If a person thinks he is infected with HIV, due to unprotected sex, and goes for a blood test. Do you think a test such as ELISA will help? If so why? If not, why?
Explain how ADA deficiency can be corrected?
A patient suffering from diabetes mellitus will have ______.
A probe which is a molecule used to locale-specific sequences in a mixture of DNA or RNA Mole cubs could be ______.
Choose the correct option regarding retrovirus.
Which of the following is the correct sequence of steps in a PCR (Polymerase Chain Reaction)?
Which of the following is not an application of PCR (Polymerase Chain Reaction)?
Now a days it is possible to detect the mutated gene causing cancer by allowing a radioactive probe to hybridize its complimentary DNA in a clone of cells, followed by its detection using autoradiography because ______
Give the full form of ELISA. Which disease can be detected using it? Discuss the principle underlying the test.
Can a disease be detected before its symptoms appear? Explain the principle involved.
What is a recombinant DNA vaccine? Give two examples.
Name the five key tools for accomplishing the tasks of recombinant DNA technology. Also mention the functions of each tool.
- Assertion: PCR is a powerful technique to identify genetic disorders.
- Reason: PCR can detect mutations in low amounts of DNA.
The diagram given below represents the schematic structure of proinsulin, which undergoes certain modifications before it becomes a fully functional insulin.
Study the diagram carefully and answer the questions that follow:
- State the change the proinsulin undergoes to become fully functional.
- Name the modern scientific technique used for the production of human insulin.
- How are the two polypeptide chains of the fully functional insulin held together?
