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प्रश्न
State the role of C-peptide in human insulin.
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उत्तर
Mammalian insulin is synthesized as a prohormone, which undergoes processing to become a fully mature and functional insulin molecule. The prohormone contains an extra chain called C-peptide, which is removed during the conversion of prohormone to the mature hormone insulin.
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संबंधित प्रश्न
Explain enzyme – replacement therapy to treat adenosine deaminase deficiency. Mention two disadvantages of this procedure.
How did an American Company, Eli Lilly use the knowledge of r-DNA technology to produce human insulin?
Suggest any two possible treatments that can be given to a patient exhibiting adenosine deaminase deficiency.
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
Expand the Given and mention one application of each:
ELISA
Explain how insulin can be produced using recombinant DNA technology.
Write any two biochemical/molecular diagonostic procedures for early detection of viral infection. Explain the principle of any one of them.
Vaccines that use components of a pathogenic organism rather than the whole organism are called ____________.
What are recombinant vaccines? Explain the types.
The hormone insulin is secreted by:
Which of the following is a neuropeptide hormone?
The site of production of ADA the body is ______.
Due to which of the following reasons insulin extracted from pancreas of slaughtered animals cannot be used in humans to treat diabetes?
Which of the following is the correct sequence of steps in a PCR (Polymerase Chain Reaction)?
For effective treatment of the disease, early diagnosis and understanding of its pathophysiology is very important. Which of the following molecular diagnostic techniques is very useful for early detection?
What is a recombinant DNA vaccine? Give two examples.
A patient is suffering from ADA deficiency. Can he be cured? How?
In the recombinant production of humulin using Escherichia coli, which plasmid vector and bacterial gene are fused with the human insulin A and B chain sequences?
Which molecular diagnostic tool relies on the hybridisation of labelled single-stranded DNA to detect specific complementary sequences or mutant alleles?
Why is the Polymerase Chain Reaction (PCR) preferred over conventional culture and serological methods for early disease diagnosis?
