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Karnataka Board PUCPUC Science 2nd PUC Class 12

What would be the molar concentration of human DNA in a human cell?

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Questions

What would be the molar concentration of human DNA in a human cell?

What would be the molar concentration of human DNA in a human cell? Consult your teacher.

Numerical
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Solution

Human diploid cell contains about 6 × 10–12 g DNA.

Human genome size ≈ 6.4 × 109 base pairs

Average mass of 1 base pair ≈ 660 g mol–1

Molar mass of DNA = 6.4 × 109 × 660

= 4.2 × 1012 g mol–1

Moles of DNA per cell = `(6xx10^-12)/(4.2xx10^12)`

= 1.4 × 10–24 mol

Taking average cell volume = 10–12 L

Concentration = `(1.4xx10^-24)/10^-12`

= 1.4 × 10–12 M

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Chapter 9: Biotechnology : Principles and Processes - EXERCISES [Page 175]

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NCERT Biology [English] Class 12
Chapter 9 Biotechnology : Principles and Processes
EXERCISES | Q 4. | Page 175
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