Question

Who accomplished the creation of the first artificial recombinant DNA molecule, and what was linked together?

Options

• Barbara McClintock linked transposable elements with chromosomal DNA in 1983

• James Watson and Francis Crick created recombinant DNA in 1953

• Frederick Sanger linked two plasmids together in 1977

• Stanley Cohen and Herbert Boyer linked a gene encoding antibiotic resistance with a native plasmid of Salmonella typhimurium in 1972

Answer 1

The first artificial recombinant DNA molecule was formed in 1972 by Stanley Cohen and Herbert Boyer by linking a gene encoding antibiotic resistance with a native plasmid of Salmonella typhimurium. This pioneering work established the foundation for modern genetic engineering and recombinant DNA technology.