Advertisements
Advertisements
Question
What is the best reagent to convert nitrile to primary amine?
Advertisements
Solution
On treatment of nitriles with strong reducing agents such as lithium aluminium hydride in either of sodium metal in alcohol, primary amines are obtained.
\[\ce{\underset{Alkyl nitrile}{R - CN} + 4[H] ->[Na/C2H5OH][or LiAH4/ether] R - Cl2NH2}\]
APPEARS IN
RELATED QUESTIONS
Write the chemical equation involved in the following reaction:
Hoffmann-bromamide degradation reaction
Give the structure of A, B and C in the following reaction:
\[\ce{C6H5N2Cl ->[CuCN] A ->[H2O/H+] B ->[NH3][\Delta] C}\]
Give the structure of A, B and C in the following reaction:
\[\ce{C6H5NO2 ->[Fe/HCl] A ->[NaNO2 + HCl][273 K] B ->[H2O/H+][\Delta] C}\]
Give the structures of A, B and C in the following reaction:
\[\ce{CH3COOH ->[NH3][\Delta] A ->[NaOBr] B ->[NaNO2/HCl] C}\]
Give the structures of A, B and C in the following reactions :
Answer the following
Explain Gabriel phthalimide synthesis.
Identify the product 'A' in the following reaction.
\[\ce{Aniline ->[(CH3CO)2O][Pyridine] A}\]
Alkyl cyanides on reduction by sodium and ethanol give primary amines. This reaction is called as ____________.
Which of the following amines forms a clear solution when treated with benzene sulphonyl chloride and excess of potassium hydroxide?
In aqueous phase the order of basic strength of alkylamine is ______.
Which of the following does NOT give carbylamine test?
The best reagent for converting, 2-phenylpropanamide into 1- phenylethanamine is ______.
Which of the following compounds is the weakest Brönsted base?
Assertion: Hoffmann’s bromamide reaction is given by primary amines.
Reason: Primary amines are more basic than secondary amines.
The compound X is which of the following?
\[\ce{CH3CN ->[Na + C2H5OH] x}\]
Identify the compo ds A and B in the following reactions:
\[\ce{A ->[Nitrating mixture] B ->[(i) Sn/cone. HCI][(ii) NaOH] Aniline}\]
Write a short note on the following:
Ammonolysis
Write a short note on the following:
Ammonolysis.
