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प्रश्न
Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (use the internet).
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उत्तर
| Recombinant protein | Therapeutic use |
| Insulin | Treatment for type I diabetes mellitus. |
| Interferon-α | Used for chronic hepatitis C. |
| Erythropoietin | Treatment of anemia. |
| Coagulation factor VIII | Treatment of haemophilia A. |
| Coagulation factor IX | Treatment of haemophilia B. |
| DNAase I | Treatment of cystic fibrosis. |
| Anti-thrombin III | Prevention of blood clots. |
| Interferon-β | For the treatment of multiple sclerosis. |
| Human recombinant growth hormone | For promoting growth in an individual. |
| Tissue plasminogen activator | Treatment of acute myocardial infarction. |
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संबंधित प्रश्न
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Read the paragraph given below and answer and questions that follow:
| Enzyme Taq polymerase, is extracted from a eubacterial microorganism Thermus aquaticus from Yellowstone National Park in Montana, USA and isolated by Chien et al. (1976). Taq polymerase successfully replaced the DNA polymerase from E.coli that was being used in PCR earlier and this shift revolutionised the PCR technique. |
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| Biotechnology revolves around the "gene of interest", with an objective to open various avenues for human welfare in health, medicine, pharma, agriculture etc. using different techniques, tools and processes. One of the breakthroughs of biotechnology in medicine is the gene therapy. |
- Name the human disease for which the gene therapy was used for the first time.
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Given below are two statements:
Statement I: The DNA fragments extracted from gel electrophoresis can be used in construction of recombinant DNA.
Statement II: Smaller size DNA fragments are observed near anode while larger fragments are found near the wells in an agarose gel.
In the light of the above statements, choose the most appropriate answer from the options given below:
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- Insertion of recombinant DNA into the host cell.
- Cutting of DNA at specific location by restriction enzyme.
- Isolation of desired DNA fragment.
- Amplification of gene of interest using PCR.
Choose the correct answer from the options given below:
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