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Question
What is the action of the following reagents on glucose?
hydroxylamine
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Solution
Glucose forms oxime by reaction with hydroxylamine:
\[\begin{array}{cc}
\phantom{}\ce{CHO}\phantom{..............}\ce{CH = N - OH}\phantom{..}\\
\phantom{.}|\phantom{..................}|\phantom{...............}\\
\ce{(CHOH)4 ->[NH2 - OH](CHOH)4 + H2O}\\
\phantom{}|\phantom{..................}|\phantom{..............}\\
\phantom{}\ce{\underset{\text{Glucose}}{CH2OH} \phantom{..........}\underset{\text{Oxime}}{CH2OH}}\phantom{........}
\end{array}\]
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