Advertisements
Advertisements
Question
Acetaldehyde, Acetone, Di-tert-butyl ketone, Methyl tert-butyl ketone (reactivity towards HCN)
Advertisements
Solution
When HCN reacts with a compound, the attacking species is a CN− nucleophile. Therefore, as the negative charge on the compound increases, its reactivity with HCN decreases. In the given compounds, the +I effect increases as shown below. It can be observed that steric hindrance also increases.
Hence, the given compounds can be arranged according to their increasing reactivities toward HCN as:
Di-tert-butyl ketone < Methyl tert-butyl ketone < Acetone < Acetaldehyde
APPEARS IN
RELATED QUESTIONS
Write balanced chemical equations for action of ammonia on - formaldehyde
Arrange the following compound in increasing order of its reactivity in nucleophilic addition reactions.
Ethanal, Propanal, Propanone, Butanone.
Hint: Consider steric effect and electronic effect.
What is meant by the following term? Give an example of the reaction in the following case.
Cyanohydrin
What is meant by the following term? Give an example of the reaction in the following case.
Oxime
What is meant by the following term? Give an example of the reaction in the following case.
2, 4-DNP-derivative
How will you bring about the following conversion in not more than two steps?
Bromobenzene to 1-Phenylethanol
Give plausible explanation for the following:
Cyclohexanone forms cyanohydrin in good yield but 2, 2, 6 trimethylcyclohexanone does not.
Complete the synthesis by giving missing starting material, reagent or product.
\[\ce{C6H5CHO ->[H2NCONHNH2]}\]
How will you convert sodium acetate to methane?
Write the main product formed when propanal reacts with the following reagents:
2 moles of 3 CH OH in presence of dry HCl
Write the main product formed when propanal reacts with the following reagents:
H2N- NH2 followed by heating with KOH in ethylene glycol.
Reaction of aqueous sodium hydroxide on chlorobenzene gives which of the following products?
The pH of blood does not appreciably change by a small addition of acid or base because
Grignard reagent on reaction with acetone forms.
Write the name of product formed, when acetone is treated with 2, 4-dinitrophenyl hydrazine.
Which will undergo faster nucleophilic addition reaction?
Acetaldehyde or Propanone
In the following reaction
\[\ce{Carbonyl compound + MeOH <=>[HCl] acetal}\]
Rate of the reaction is the highest for ______.
Draw structure of the following derivative.
The ethylene ketal of hexan-3-one
Draw structures of the given derivatives.
The ethylene ketal of hexan-3-one
Draw the structure of the given derivative.
The ethylene ketal of hexan-3-one
