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Revision: Reproduction >> Human Reproduction Biology Science (English Medium) Class 12 CBSE

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Definitions [24]

Definition: Reproduction

Reproduction is a process that results in the formation of new individuals of the same kind, though usually with slight genetic, structural and physiological variations.

Define the term puberty.

Puberty is the process of physical and hormonal changes by which a child’s body matures into an adult body capable of sexual reproduction to enable fertilization.

Definition: Ejaculation

The process of expulsion of semen from the urethra is called ejaculation.

Define Spermatogenesis.

Spermatogenesis is the process of formation and development of sperm cells (spermatozoa) in the testes from spermatogonial stem cells through mitosis and meiosis.

Define the following term: 

Hernia

Hernia is an abnormal condition that is caused when the intestine, due to the pressure in the abdomen, bulges into the scrotum through the inguinal canal.

Definition: Seminal Fluid or Semen

The secretion of glands with spermatozoa is a whitish viscous fluid known as seminal fluid or semen.

Define the following term:

Hymen

The opening of the vagina in young females is partially closed by a thin membrane called the hymen (or virgin knot).

Define gametogenesis.

Gametogenesis is the process of formation of gametes i.e., sperms and ovary from the primary sex organs in all sexually reproducing organisms. Meiosis plays the most significant role in the process of gametogenesis.

Define spermiogenesis.

Spermiogenesis is the process of transforming spermatids into mature, flagellated spermatozoa (sperms).

The process of transformation of a circular spermatid to a spermatozoon is called spermiogenesis.

Definition: Gametogenesis

Gametogenesis is the process by which male and female primary sex organs produce gametes (sperms and ova).

or

Gametogenesis is the process by which male and female gametes are formed from germinal cells in the gonads through a series of developmental stages.

Define spermiation.

Spermiation is the process of releasing mature spermatozoa. In this, spermatozoa are shed into the lumen of the seminiferous tubule for transport.

After spermiogenesis, sperm heads become embeded in sertoli cells from which they obtain their nutrition and finally get released into the lumen of seminiferous tubules. This process of release of mature sperms from sertoli cells is called spermiation.

Definition: Spermatogenesis

Formation of haploid sperms (male gametes) from diploid spermatogonia (sperm mother cells) is called spermatogenesis.

Definition: Spermiation

The process of release of mature sperms from Sertoli cells into the lumen of seminiferous tubules is called spermiation.

or

Spermiogenesis (also called spermateleosis) is the process of transformation (metamorphosis) of spermatids into mature spermatozoa (sperms).

Definition: Oogenesis

The formation of ova in the ovary from primordial germinal cells is said to be oogenesis.

Definition: Menstrual Cycle

The rhythmic series of changes in the sex organs throughout the reproductive life of a female primate (e.g., monkeys, apes, and human beings) from puberty to menopause is called the menstrual cycle (L. mensis = month, lunar month).

Define ovulation.

The release of the ovum from the ovary is called ovulation.

Define: Menarche

It is the stage when a girl menstruates for the first time.

Define.

Fertilization

The formation of a zygote by the union of male and female gametes is known as fertilization.

Definition: Fertilization in Human

The fusion of the male gamete (sperm) and female gamete (ovum) to form a zygote is called fertilisation.

or

Formation of a zygote by the union of a sperm and an ovum is called fertilisation.

Definition: Implantation

The process of the blastocyst embedding itself into the endometrial lining of the uterus about 5–7 days after ovulation is called implantation.

or

The process of fixing of the blastocyst to the wall of the uterus/endometrium is termed implantation.

Definition: Gastrulation

Gastrulation is the early developmental process in which the embryo changes from a single-layered blastula into a three-layered structure called the gastrula.

Definition: Placenta

Placenta is a temporary organ formed during pregnancy that connects the foetus to the uterine wall and allows exchange of nutrients, gases and wastes between the mother and the foetus.

Definition: Parturition

After nine months of pregnancy, the fully developed foetus is ready for delivery. The process of childbirth is called parturition.

or

Parturition is the act of expelling the full term foetus from the mother's uterus at the end of gestation.

Definition: Lactation

The term lactation refers to the secretion and ejection of milk by the mammary glands.

Key Points

Key Points: Human Reproduction
  • Humans are sexually reproducing and viviparous (give birth to young ones, not eggs).
  • 6 stages of reproduction in order: Gametogenesis → Insemination → Fertilisation → Implantation → Gestation → Parturition.
  • Gametogenesis (gamete formation), Insemination (sperm transfer), Fertilisation (fusion → zygote), Implantation (blastocyst attaches to uterine wall), Gestation (embryo development), Parturition (delivery of baby).
  • Sperm formation continues throughout a man's life; ovum formation ceases at around age fifty (menopause) in women.
  • Testes (males) produce sperm; Ovaries (females) produce eggs; these are the primary reproductive organs (gonads).
  • Features like beard (males) and breasts (females) are secondary sexual characters; they do not directly participate in reproduction.
Key Points: Male Reproductive System
  • The male reproductive system is located in the pelvic region and includes testes, accessory ducts, accessory glands, and external genitalia (penis and scrotum).
  • Testes are the primary sex organs present in the scrotum; they contain seminiferous tubules where sperm are produced, while Leydig cells secrete testosterone, and Sertoli cells provide nourishment.
  • Accessory ducts—rete testis → vasa efferentia → epididymis → vas deferens → ejaculatory duct → urethra—help in storage, maturation, and transport of sperm.
  • Accessory glands—seminal vesicles, prostate gland, and bulbourethral glands—add secretions like fructose, enzymes, and mucus, which nourish sperms and aid in their movement.
  • The penis acts as the external genital organ, containing the urethra, and helps in the transfer of sperm during ejaculation.
Key Points: The Female Reproductive System
  • Includes - Ovaries, Fallopian tubes, Uterus, Cervix, Vagina, External genitalia, Bartholin's glands, Mammary glands - all in the pelvic region.
  • Ovaries - outer cortex (follicles) + inner medulla; produce ova and ovarian hormones; release one ovum monthly after puberty.
  • Fallopian tube - 3 parts: Infundibulum (fimbriae collect ovum) → Ampulla (site of fertilisation) → Isthmus (connects to uterus); cilia push egg towards uterus.
  • Uterus - 3 layers: Perimetrium (outer), Myometrium (muscular), Endometrium (inner, menstrual changes); opens into vagina via cervix (birth canal).
  • Zygote implants in the endometrium; the placenta connects the embryo to the mother for nutrient and waste exchange till birth.
  • External genitalia - Mons pubis, Labia majora, Labia minora, Hymen, Clitoris. Bartholin's glands provide lubrication.
  • Mammary glands - produce milk for newborns. Puberty begins at 10–14 years in females.
Key Points: Gametogenesis
  • Gametogenesis is the process of formation of male and female gametes in the reproductive organs.
  • It occurs in the testes of males and ovaries of females.
  • Spermatogenesis produces sperms, while oogenesis produces ova (eggs).
  • In this process, diploid germ cells form haploid gametes for sexual reproduction.
Key Points: Phases of Spermatogenesis
Phase Main Process Key Features
Multiplication phase Mitotic division of germ cells Spermatogonia (2n) multiply under FSH; Type A continue dividing, Type B become sperm mother cells
Growth phase Increase in cell size Type B spermatogonia grow and form primary spermatocytes (2n) by accumulating nutrients
Maturation phase Meiotic divisions Primary spermatocyte → secondary spermatocytes (n) → four haploid spermatids (n)
Key Points: Structure of Sperms
Part of Sperm Structure Major Components Function
Head Conical Haploid nucleus, acrosome Carries genetic material; enzymes help in fertilization
Neck Short region Proximal and distal centrioles Connects head to tail; initiates zygote division
Middle piece Cylindrical Axial filament, mitochondrial sheath Supplies energy for movement
Tail Long flagellum Axial filament, plasma membrane Locomotion of sperm
Key points:
  • Spermiogenesis is the process by which spermatids are transformed into mature spermatozoa (sperms).
  • During spermiogenesis, the nucleus becomes condensed, the acrosome develops, and the tail is formed.
  • Mitochondria arrange around the middle piece to supply energy for sperm movement.
  • The mature sperm becomes specialised for motility and fertilisation of the ovum.
  • One primary spermatocyte finally produces four sperms after meiosis and spermiogenesis.
  • The release of mature sperms from Sertoli cells into the lumen of seminiferous tubules is called spermiation.
Key Points: Phases of Oogenesis
Phase Cells Involved Key Events Outcome
Multiplication phase Germinal epithelium cells Mitotic divisions form follicles; one cell differentiates into an oogonium Formation of oogonia
Growth phase Oogonium → Primary oocyte Cell enlarges and accumulates nutrients; remains diploid Formation of a primary oocyte
Maturation phase Primary & secondary oocyte Meiosis I forms a secondary oocyte + polar body; Meiosis II completes only after fertilisation Formation of the haploid ovum and polar bodies
Key Points: Menstrual Cycle (Ovarian Cycle)
  • The menstrual cycle is a series of monthly changes in females of reproductive age.
  • The beginning of the cycle is called menarche, and its permanent stop is called menopause (around 45–50 years).
  • It occurs mainly in primates, including humans, and involves changes in the ovaries and uterus.
  • The cycle is controlled by hormones (gonadotropins and ovarian hormones) and repeats every ~28 days.
  • In the middle of the cycle, ovulation occurs, where an egg is released from one of the ovaries.
Key Points: Major Events of Menstrual Cycle
Phase of Menstrual Cycle Duration (Days) Hormonal Changes Major Events
Menstrual phase (Bleeding phase) 1–5 Decrease in estrogen and progesterone due to degeneration of corpus luteum Shedding of endometrium with blood, mucus and unfertilized ovum
Proliferative phase (Follicular phase) 6–13 Gradual increase in FSH, LH and estrogen Growth of Graafian follicle; regeneration and thickening of endometrium
Ovulatory phase 14 LH surge (peak of LH and FSH) Rupture of Graafian follicle and release of ovum (ovulation)
Secretory phase (Luteal phase) 15–28 Increased progesterone from corpus luteum Endometrium becomes vascular and glandular; prepares for implantation; corpus luteum degenerates if no fertilization
Key Points: Menstrual Hygiene
  • Maintain proper hygiene during menstruation to prevent infections.
  • Keep the pubic area clean by washing regularly.
  • Change sanitary napkins every 4–5 hours or as needed.
  • Use clean and dry sanitary products; avoid damp or dirty cloths.
  • Dispose of used sanitary napkins properly in a hygienic manner.
  • Poor hygiene or prolonged use of napkins can lead to the growth of harmful bacteria and infections.
Key Points: Fertilisation in Human
  • Fertilisation in humans is the fusion of male and female gametes (sperm and ovum) and is an internal process occurring in the oviduct, leading to the formation of a diploid zygote.
  • During copulation, millions of sperms are released into the vagina, but only one sperm reaches the ovum due to selection and protective barriers around the egg.
  • Before fertilisation, sperm undergo capacitation and move towards the ovum; interaction between sperm and egg involves recognition molecules like fertilizin (ovum) and antifertilizin (sperm).
  • The sperm’s acrosome releases enzymes that help digest the egg coverings (corona radiata and zona pellucida), allowing sperm entry through the membrane.
  • After entry, the sperm nucleus and the ovum nucleus fuse (syngamy), forming a zygote (2n); this process restores the diploid chromosome number (46 in humans).
  • Fertilisation triggers completion of meiosis II in the oocyte, formation of the second polar body, and formation of the female pronucleus and male pronucleus.
  • In humans, sperm carry 22+X or 22+Y chromosomes, while ova carry 22+X only, determining the genetic sex of the offspring.
Key Points: Implantation in Human
  • The zygote divides by mitosis (cleavage) while moving towards the uterus.
  • It forms blastomeres, and the 8–16 cell stage is called morula.
  • Morula develops into a blastocyst with trophoblast (outer layer) and inner cell mass.
  • Trophoblast attaches to the uterine lining (endometrium), and the inner cell mass forms the embryo.
  • Implantation is the embedding of the blastocyst into the endometrium, leading to pregnancy.
Key Points: Pregnancy and Embryonic Development
  • Placenta is formed after implantation and helps in exchange of nutrients, oxygen and wastes between mother and foetus.
  • Three germ layers (ectoderm, mesoderm and endoderm) are formed, which develop into all body organs.
  • Hormones like hCG, progesterone and estrogen increase to support pregnancy and foetal growth.
  • Foetal development occurs gradually, and by nine months the foetus is fully developed and ready for birth.
Key Points: Parturition (Birth) in Human
  • Parturition is the process of childbirth, i.e., the delivery of the foetus at the end of the gestation period.
  • It is controlled by a neuro-endocrine mechanism involving signals from the fully developed foetus and placenta.
  • Foetal signals trigger uterine contractions known as the foetal-ejection reflex (labour pain).
  • Hormones like ACTH and corticosteroids from the foetus stimulate the release of oxytocin from the mother’s pituitary gland.
  • Parturition occurs in three stages: dilation, expulsion of the baby, and after birth (placenta removal).
Key Points: Lactation in Human
  • Lactation is the process by which mammary glands produce milk at the end of pregnancy, under the influence of the hormone Prolactin.
  • The first milk secreted soon after childbirth is called Colostrum - it is sticky, yellowish and rich in proteins, lactose and antibodies (IgA); fat content is low.
  • Antibodies (especially IgA) in colostrum provide passive immunity to the newborn when its own immune system is not yet fully developed.
  • Lactation helps the mother in feeding and nourishing the newborn baby, providing all essential nutrients required in early life.

Important Questions [47]

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