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प्रश्न
Explain the following reaction with a suitable example.
Hofmann elimination reaction
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उत्तर
- When tetraalkylammonium halide is heated with moist silver oxide, it gives quaternary ammonium hydroxide.
- Quaternary ammonium hydroxides on strong heating undergo β-elimination to give an alkene. This reaction is called Hofmann elimination.
- The least substituted alkene is obtained as a major product (in contrast to Saytzeff elimination).
e.g. Hofmann elimination reaction of N, N, N-Triethylpropylammonium iodide
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संबंधित प्रश्न
Write the chemical equation involved in the following reaction:
Hoffmann-bromamide degradation reaction
An aromatic compound 'A' of molecular formula C7H7ON undergoes a series of reactions as shown below. Write the structures of A, B, C, D and E in the following reactions :
How do you convert the following: Ethanenitrile to ethanamine
Write a short note on the following:
Hoffmann’s bromamide reaction
Accomplish the following conversion:
Benzyl chloride to 2-phenylethanamine
Give the structure of A, B and C in the following reaction:
\[\ce{CH3CH2I ->[NaCN] A ->[OH-][Partial hydrolysis] B ->[NaOH + Br2] C}\]
Give the structure of A, B and C in the following reaction:
\[\ce{C6H5N2Cl ->[CuCN] A ->[H2O/H+] B ->[NH3][\Delta] C}\]
Give the structures of A, B and C in the following reaction:
\[\ce{CH3COOH ->[NH3][\Delta] A ->[NaOBr] B ->[NaNO2/HCl] C}\]
Give the structures of A, B and C in the following reactions :
Write structures of compounds A and B in each of the following reactions:
Choose the most correct option.
Which of the following compounds will dissolve in aqueous NaOH after undergoing reaction with Hinsberg reagent?
Answer in one sentence.
Which amide does produce ethanamine by Hofmann bromamide degradation reaction?
Answer the following
Write a reaction to convert acetic acid into methylamine.
Answer the following
Explain the ammonolysis of alkyl halides.
The following amines is the product of Gabriel phthalimide synthesis.
Write the order of reactivity of alkyl halides with ammonia.
Explain Hoffmann’s exhaustive alkylation with suitable reactions.
Why cannot aniline be prepared by Gabriel phthalimide synthesis?
Identify the product 'A' in the following reaction.
\[\ce{Aniline ->[(CH3CO)2O][Pyridine] A}\]
The end product C of the following reaction is
\[\ce{C2H5NH2 ->[HNO2] A ->[PCl5] B ->[NH3][Alcohol] C}\]
Identify the product obtained, when benzamide is treated with bromine and aqueous sodium hydroxide.
Identify the product obtained when benzyl chloride undergoes ammonolysis in presence of excess ammonia followed by the reaction with two moles of methyl iodide.
What product is formed when \[\ce{R - C ≡ N}\] is hydrolysed?
\[\ce{CH3-CN ->[Na/C2H5OH]}\]
The product formed is ____________.
Which nitrogen containing compound amongst the following would undergo Mendius reduction to furnish primary amine \[\ce{(R - NH2)}\]?
Which of the following reactions does NOT yield an amine?
For producing amines, the reaction of nitro compounds with iron scrap is preferred because:
Given below are two statements labelled as Assertion (A) and Reason (R).
Assertion (A): Alkyl halides are insoluble in water.
Reason (R): Alkyl halides have halogen attached to sp3 hybrid carbon.
Select the most appropriate answer from the options given below:
Amongst the following, the strongest base in aqueous medium is ______.
Reduction of aromatic nitro compounds using \[\ce{Fe}\] and \[\ce{HCl}\] gives ______.
Reduction of nitrobenzene by which of the following reagent gives aniline?
(i) \[\ce{Sn/HCl}\]
(ii) \[\ce{Fe/HCl}\]
(iii) \[\ce{H2 - Pd}\]
(iv) \[\ce{Sn/NH4OH}\]
The reagents that can be used to convert benzenediazonium chloride to benzene are:
(i) \[\ce{SnCl2/HCl}\]
(ii) \[\ce{CH3CH2OH}\]
(iii) \[\ce{H3PO2}\]
(iv) \[\ce{LiAlH4}\]
Which of the following amines can be prepared by Gabriel synthesis.
(i) Isobutyl amine
(ii) 2-Phenylethylamine
(iii) N-methylbenzylamine
(iv) Aniline
What is the product when \[\ce{C6H5CH2NH2}\] reacts with \[\ce{HNO2}\]?
What is the best reagent to convert nitrile to primary amine?
How will you carry out the following conversions?
Reduction of nitro alkanes yields which compound?
In the given reaction what is the X?
\[\begin{array}{cc}
\ce{O}\phantom{.......................}\\
||\phantom{.......................}\\
\phantom{}\ce{R - C - OH <-[H3O] Χ ->[H] RCH2NH2}
\end{array}\]
Acetamide and ethyl amide can be distinguished by reacting with.
Give reasons for the following:
Ammonolysis of alkyl halides is not a good method to prepare pure primary amines.
Which of the following compound gives pink colour on reaction with phthalic anhydride in cone. H2SO4 followed by treatment with NaOH?
Identify the product ‘C’ in the following reaction.
\[\ce{Aniline ->[(CH3CH)2O][Pyridine] A ->[Br2][CH3COOH] B ->[H^+ or OH^-] C}\]
Write the name of the product formed by the action of LiAlH4/ether on acetamide.
Write short note on the following:
Ammonolysis
Write short note on the following:
Ammonolysis
Write a short note on the following:
Ammonolysis
Write short note on the following.
Ammonolysis.
Write a short note on the following:
Ammonolysis.
