Advertisements
Advertisements
प्रश्न
Explain the following reaction with a suitable example.
Hofmann elimination reaction
Advertisements
उत्तर
- When tetraalkylammonium halide is heated with moist silver oxide, it gives quaternary ammonium hydroxide.
- Quaternary ammonium hydroxides on strong heating undergo β-elimination to give an alkene. This reaction is called Hofmann elimination.
- The least substituted alkene is obtained as a major product (in contrast to Saytzeff elimination).
e.g. Hofmann elimination reaction of N, N, N-Triethylpropylammonium iodide
APPEARS IN
संबंधित प्रश्न
How is ethyl amine prepared from methyl iodide?
How are propan-1-amine and propan-2-amine prepared from oxime?
Write the chemical equation involved in the following reaction:
Hoffmann-bromamide degradation reaction
How do you convert the following: C6H5CONH2 to C6H5NH2
Accomplish the following conversion:
Nitrobenzene to benzoic acid
Give the structures of A, B and C in the following reaction:
\[\ce{C6H5NO2 ->[Fe/HCl] A ->[HNO2][273 K] B ->[C6H5OH] C}\]
Why cannot aromatic primary amines be prepared by Gabriel phthalimide synthesis?
Write the reaction of aromatic primary amine with nitrous acid.
Give a plausible explanation for the following:
Why are amines less acidic than alcohols of comparable molecular masses?
Give the structures of A, B and C in the following reactions :
Give the structures of A, B and C in the following reactions :
Write structures of compounds A and B in each of the following reactions:
Answer in one sentence.
Which amide does produce ethanamine by Hofmann bromamide degradation reaction?
Answer the following
Identify A and B in the following reactions.
\[\ce{C6H5CH2Br->[alco.][KCN]A ->[Na/ethanol]B.}\]
Answer the following
Write a reaction to convert acetic acid into methylamine.
Answer the following
Explain Gabriel phthalimide synthesis.
Answer the following
Explain the ammonolysis of alkyl halides.
Write reactions to prepare ethanamine from Acetonitrile.
The following amines is the product of Gabriel phthalimide synthesis.
Name the process of breaking C-X bond by ammonia in preparation of amines.
Write the order of reactivity of alkyl halides with ammonia.
Write reactions to bring about the following conversions.
Acetamide to Ethylamine
Identify the product 'A' in the following reaction.
\[\ce{Aniline ->[(CH3CO)2O][Pyridine] A}\]
Identify the major product (B).
What is the molar mass of the amine formed when acetamide undergoes Hofmann bromamide degradation?
Which nitrogen containing compound amongst the following would undergo Mendius reduction to furnish primary amine \[\ce{(R - NH2)}\]?
Identify the product obtained when benzamide is treated with bromine and aqueous sodium hydroxide?
The reduction of alkyl cyanide with sodium and ethanol to give primary amines is, ____________.
Which of the following reagents is used in Mendius reduction reaction of alkyl cyanide?
Identify product B in the following reaction.
\[\ce{Aniline ->[NaNO2][HCl] A ->[KI] B}\]
Which of the following reagents is used in Hofmann's elimination reaction of amines?
Which of the following compounds is obtained when quaternary ammonium hydroxide is strongly heated?
Amongst the following, the strongest base in aqueous medium is ______.
Which of the following reagents would not be a good choice for reducing an aryl nitro compound to an amine?
The best reagent for converting 2–phenylpropanamide into 2-phenylpropanamine is ______.
The best reagent for converting, 2-phenylpropanamide into 1- phenylethanamine is ______.
Reduction of aromatic nitro compounds using \[\ce{Fe}\] and \[\ce{HCl}\] gives ______.
Which of the following compounds is the weakest Brönsted base?
Which of the following methods of preparation of amines will give same number of carbon atoms in the chain of amines as in the reactant?
Which of the following reactions are correct?
(i)
(ii)
(iii)
(iv)
Under which of the following reaction conditions, aniline gives p-nitro derivative as the major product?
(i) Acetyl chloride/pyridine followed by reaction with conc.\[\ce{H2SO4 }\] + conc. \[\ce{HNO3}\].
(ii) Acetic anyhdride/pyridine followed by conc.\[\ce{H2SO4}\] + conc.\[\ce{HNO3}\].
(iii) Dil. HCl followed by reaction with conc.\[\ce{H2SO4}\] + conc.\[\ce{HNO3}\].
(iv) Reaction with conc.\[\ce{HNO3}\] + conc.\[\ce{H2 SO4}\].
What is the best reagent to convert nitrile to primary amine?
Identify A and B in the following reaction.
How will you bring out the following conversion?
How will you carry out the following conversions?
Which of the following reactions will not give a primary amine?
In the given reaction what is the X?
\[\begin{array}{cc}
\ce{O}\phantom{.......................}\\
||\phantom{.......................}\\
\phantom{}\ce{R - C - OH <-[H3O] Χ ->[H] RCH2NH2}
\end{array}\]
Acetamide and ethyl amide can be distinguished by reacting with.
Which of the following CANNOT be prepared by ammonolysis of alkyl halide?
Which of the following compound gives pink colour on reaction with phthalic anhydride in cone. H2SO4 followed by treatment with NaOH?
The amine 'A' when treated with nitrous acid gives yellow oily substance. The amine A is ______.
Which of the following statement(s) is/are incorrect in case of Hofmann bromamide degradation?
Which of the following would not be a good choice for reducing nitrobenzene to aniline?
Amides can be converted into amines by the reaction named ______.
Write the name of reduction product formed when ethyl cyanide is treated with sodium and alcohol.
