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Biology 57-1-2 2025-2026 Science (English Medium) Class 12 Question Paper Solution

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Biology [57-1-2]
Marks: 70 CBSE
Science (English Medium)

Academic Year: 2025-2026
Date & Time: 27th March 2026, 10:30 am
Duration: 3h
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Note:

  1. Please check that this question paper contains 23 printed pages.
  2. Q.P. Code given on the right hand side of the question paper should be written on the title page of the answer-book by the candidate.
  3. Please check that this question paper contains 33 questions.
  4. Please write down the serial number of the question in the answer-book at the given place before attempting it.
  5. 15 minute time has been allotted to read this question paper. The question paper will be distributed at 10.15 a.m. From 10.15 a.m. to 10.30 a.m., the candidates will read the question paper only and will not write any answer on the answer-book during this period.

General Instructions:

Read the following instructions carefully and follow them:

  1. This question paper contains 33 questions. All questions are compulsory.
  2. Question paper is divided into FIVE sections - Section A, B, C, D and E.
  3. Section A - questions number 1 to 16 are multiple choice type questions. Each question carries 1 mark.
  4. Section B - questions number 17 to 21 are very short answer type questions. Each question carries 2 marks.
  5. Section C - questions number 22 to 28 are short answer type questions. Each question carries 3 marks.
  6. Section D - questions number 29 and 30 are case-based questions. Each question carries 4 marks. Each question has subparts with internal choice in one of the subparts.
  7. Section E - questions number 31 to 33 are long answer type questions. Each question carries 5 marks.
  8. There is no overall choice. However, internal choices have been provided in some questions. A candidate has to write answer for only one of the alternatives in such questions.
  9. Kindly note that there is a separate question paper for Visually Impaired candidates.
  10. Wherever necessary, neat and properly labelled diagrams should be drawn.

SECTION - A
Question Nos. 1 to 16 are Multiple Choice Type Questions, carrying 1 mark each. Choose the best option.
[1]1.

Match Column - I with Column - II and choose the correct option:

  Column - I   Column - II
a. Biolistic gun i. Bacterial cell
b. Chitinase ii. Tumour inducing
c. Ti iii. Animal cell
d. Ca++ iv. Fungal cell
    v. Plant cell

a - i, b - ii, c - iii, d - iv

a - ii, b - v, c - i, d - iii

a - v, b - iv, c - ii, d - i

a - v, b - i, c - iv, d - ii

Concept: undefined - undefined
Chapter:
[1]2.

Microbes commonly used in kitchen are ______.

Lactobacillus and Yeast

Penicillium and Yeast

Microspora and E. coli

Rhizopus and Lactobacillus

Concept: undefined - undefined
Chapter:
[1]3.

The features of some structures of human male reproductive system are given below. Choose the correct option that matches the features with the structures.

  1. It opens into the Vasa efferentia through rete testis.
  2. It carries semen as well as urine.
  3. It maintains temperature (2 – 2.5°C) lower than body temperature for sperm formation.
  4. It leads to vas deferens that ascends to the abdomen.

(i) - Seminal vesicle, (ii) - Urethra, (iii) - Scrotum, (iv) - Seminiferous tubule

(i) - Prostrate, (ii) - Scrotum, (iii) - Testes, (iv) - Vas Deferens

(i) - Seminiferous tubule, (ii) - Urethra, (iii) - Scrotum, (iv) - Epididymis

(i) - Seminiferous tubule, (ii) - Vas Deferens, (iii) - Urethra, (iv) - Sertoli cells

Concept: undefined - undefined
Chapter:
[1]4.

Exploration of molecular, genetic and species level diversity for gaining products of economic importance is called ______.

Exploitation

Bio-prospecting

Bio-patenting

Bio-piracy

Concept: undefined - undefined
Chapter:
[1]5.

Which connective tissue connects ovary to pelvic wall and uterus?

Tendons

Ligaments

Cartilage

Bone

Concept: undefined - undefined
Chapter:
[1]6.

Which of the following is not a component of detritus food chain?

Dead Leaves

Bacteria

Fungi

Zooplankton

Concept: undefined - undefined
Chapter:
[1]7.

Identify the plant in which emasculation is not required for artificial hybridization.

Rice

Wheat

Pea

Papaya

Concept: undefined - undefined
Chapter:
[1]8.

Pomato was produced by fusing protoplasts of ______.

Tomato and Potato

Pomegranate and Tomato

Pomegranate and Potato

Pomegranate, Potato and Tomato

Concept: undefined - undefined
Chapter:
[1]9.

Which of the following sacred groves is found in Meghalaya?

Jaintia hills

Bastar

Chanda

Sarguja

Concept: undefined - undefined
Chapter:
[1]10.

Messelson and Stahl’s experiment carried out centrifugation in CsCl2 density gradient to separate ______.

DNA from RNA

DNA from protein

RNA from protein

Normal DNA from heavy DNA

Concept: undefined - undefined
Chapter:
[1]11.

Which one of the following is not a component required for Polymerase Chain Reaction (PCR)?

Template DNA

Primers

DNA Ligase

DNA Polymerase

Concept: undefined - undefined
Chapter:
[1]12.

In the following figure, two ways of pairing of two homologous pairs of chromosomes are shown. Which of the following phenomena is expressed?

Linkage of genes

Independent assortment of genes

Multiple alleles

Incomplete dominance

Concept: undefined - undefined
Chapter:
For Questions number 13 to 16, two statements are given - one labelled as Assertion (A) and the other labelled as Reason (R). Select the correct answer to these questions from the codes (A), (B), (C) and (D) given below:
[1]13.

Assertion (A): When we see stars, we are apparently peeping into the past.

Reason (R): What we see today is an object whose emitted light started its journey millions of years back reaching our eyes now.

Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation for Assertion (A).

Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation for Assertion (A).

Assertion (A) is true, but Reason (R) is false.

Assertion (A) is false, but Reason (R) is true.

Concept: undefined - undefined
Chapter:
[1]14.

Assertion (A): Flocs are masses of bacteria associated with fungal filaments in secondary treatment of sewage.

Reason (R): Flocs help in digestion of solid waste by anaerobic respiration.

Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation for Assertion (A).

Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation for Assertion (A).

Assertion (A) is true, but Reason (R) is false.

Assertion (A) is false, but Reason (R) is true.

Concept: undefined - undefined
Chapter:
[1]15.

Assertion (A): In terrestrial ecosystem much larger fraction of energy flows through grazing food chain.

Reason (R): Grazing food chain may be connected to Detritus food chain at some levels.

Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation for Assertion (A).

Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation for Assertion (A).

Assertion (A) is true, but Reason (R) is false.

Assertion (A) is false, but Reason (R) is true.

Concept: undefined - undefined
Chapter:
[1]16.

Assertion (A): The milk produced by transgenic cow Rosie’ was nutritionally more balanced product for human babies than natural cow milk.

Reason (R): It was human protein enriched milk containing human alpha lactaglobulin.

Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation for Assertion (A).

Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation for Assertion (A).

Assertion (A) is true, but Reason (R) is false.

Assertion (A) is false, but Reason (R) is true.

Concept: undefined - undefined
Chapter:
SECTION - B
[2]17.
[1]17. (a)

What is the role of LAB (Lactic Acid Bacteria) in preparation of curd?

Concept: undefined - undefined
Chapter:
[1]17. (b)

Mention two health benefits of consuming curd.

Concept: undefined - undefined
Chapter:
[2]18. (a)
[1]18. (a) i.

Name the muscular layers of the female uterus. Mention one function.

Concept: undefined - undefined
Chapter:
[1]18. (a) ii.

Name the glandular layers of the female uterus. Mention one function.

Concept: undefined - undefined
Chapter:
OR
[2]18. (b)
[1]18. (b) (i)

Why are STI (Sexually Transmitted Infections) not detected in time?

Concept: undefined - undefined
Chapter:
[1]18. (b) (ii)

Write two complications caused in later stages.

Concept: undefined - undefined
Chapter:
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[2]19.
[1]19. (a)

Write the importance of following in biotechnology:

Ori (Origin of Replication)

Concept: undefined - undefined
Chapter:
[1]19. (b)

Write the importance of following in biotechnology:

Enzyme Polymerase used in Polymerase Chain Reaction

Concept: undefined - undefined
Chapter:
[2]20. (a)
[1]20. (a) (i)

Given below is a pyramid found in an ecosystem, where each bar represents the standing crop available in the trophic level.

Identify the kind of pyramid and with the help of an example explain the conditions where this kind of pyramid is possible in nature.

Concept: undefined - undefined
Chapter:
[1]20. (a) (ii)

Given below is a pyramid found in an ecosystem, where each bar represents the standing crop available in the trophic level.

Write any two limitations of ecological pyramids.

Concept: undefined - undefined
Chapter:
OR
[2]20. (b)
[1]20. (b) (i)

In an ecosystem there was loss of biodiversity due to some project in that area.

How will biodiversity be affected?

Concept: undefined - undefined
Chapter:
[1]20. (b) (ii)

In an ecosystem there was loss of biodiversity due to some project in that area.

List two major causes of loss of biodiversity.

Concept: undefined - undefined
Chapter:
[2]21. (a)
[1]21. (a) i.

Analyse the following case of sex determination in different organisms:

Males have (XO) sex chromosomes and females have two copies of same sex chromosome (XX).

Identify the type of heterogamety in this case and provide one example.

Concept: undefined - undefined
Chapter:
[1]21. (a) ii.

Analyse the following case of sex determination in different organisms:

Females have two different sex chromosomes (ZW) and males have two copies of same sex chromosome (ZZ).

Identify the type of heterogamety in this case and provide one example.

Concept: undefined - undefined
Chapter:
OR
[2]21. (b)
[1]21. (b) (i)

Differentiate between a DNA and a RNA nucleotide.

Concept: undefined - undefined
Chapter: [5] Molecular Basis of Inheritance
[1]21. (b) (ii)

Name the two types of bonds present within a single nucleotide.

Concept: undefined - undefined
Chapter:
SECTION - С
[3]22.

A farmer grew two varieties of corn crop in field A and B. He grew normal corn crops in field A and GM corn crops in field B.

He observed that corn borers attacked only in field A. To control it, spores of Bt were sprayed on field A.

  1. Name the gene in the spores responsible for control of pest.     [0.5]
  2. What effect will the spores of Bt have on insect pest?     [1.5]
  3. How has corn plants of field B developed resistance against this pest? Explain.     [1]
Concept: undefined - undefined
Chapter:
[3]23.

Observe the given picture carefully. A mixture of DNA with fragments ranging from 100 base pairs to 1800 base pairs were separated by electrophoresis on agarose gel with the following arrangement:

  1. What result will be obtained in staining with ethidium bromide? Explain with reasons.     [1]
  2. The above setup was modified as shown below and a band with 100 base pairs was obtained at X.

    What changes were made to the previous design to get a band at ‘X’. Why did the band appear at ‘X’?     [2]
Concept: undefined - undefined
Chapter:
[3]24.
[1]24. (a)

Write the scientific name of the source plant and the part from which opiods are extracted. What is it commonly and chemically called?

Concept: undefined - undefined
Chapter: [7] Human Health and Diseases
[1]24. (b) i.

How are morphine and heroin related?

Concept: undefined - undefined
Chapter:
[1]24. (b) ii.

Mention the effect of morphine and heroin on the human body.

Concept: undefined - undefined
Chapter:
[3]25.
  1. Give a schematic representation of oogenesis in human females.
  2. Mention the number of chromosomes at each stage. Correlate the life phases of the individual with the stages of the process.
Concept: undefined - undefined
Chapter:
[3]26.
[2.5]26. (a)

Do all pollen grains remain viable for the same length of time? Support your answer with two suitable examples.

Concept: undefined - undefined
Chapter:
[0.5]26. (b)

How are pollen grains stored in pollen banks?

Concept: undefined - undefined
Chapter:
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[3]27.
[1]27. (a) i.

What is pedigree analysis?

Concept: undefined - undefined
Chapter:
[1]27. (a) ii.

Mention the importance of pedigree analysis in human genetics.

Concept: undefined - undefined
Chapter:
[1]27. (b)

Analyse the following pedigree and write the

  1. Pattern of inheritance.     [0.5]
  2. Give one example of disease showing such an inheritance pattern.     [0.5]

Concept: undefined - undefined
Chapter:
[3]28.
[2]28. (a)

How is Hardy-Weinberg’s expression “(p2 + 2pq + q2) = 1” derived?

Concept: undefined - undefined
Chapter: [6] Evolution
[1]28. (b)

List any two factors that can disturb the genetic equilibrium.

Concept: undefined - undefined
Chapter: [6] Evolution
SECTION - D
Question Nos. 29 and 30 are case-based questions. Each question has subsections with internal choice in one sub-section.
[5]29.

A student performed some crosses in plants and represented the result in the form of bar graphs as shown below. Each graph displays the phenotypic proportion of the progeny. Study the graphs and answer the questions:

(a) What can you infer about the genotype of parents in crosses I and II?     [1]

OR

(a) Which genetic cross is represented by these crosses?     [1]

(b) Looking at bar graph of cross III, identify the type of cross performed and its importance in genetics.     [2]

(c) What conclusion can you draw from the results of bar graphs of crosses I and II? Name the genetic principle illustrated.     [1]

Concept: undefined - undefined
Chapter:
[5]30.

The diagram below shows the distribution of two barnacle species, Chthamalus and Balanus on a rocky sea shore.

When Balanus is experimentally removed, Chthamalus expands its range in lower intertidal zone.

(a) Identify and define the ecological phenomenon demonstrated by this observation.     [1]

OR

(a) State the principle that explains the elimination of one species.     [1]

(b) Two different species can compete for the same resource. Give another example of it.     [1]

(c) How do species avoid competition in nature? Explain with an example.     [2]

Concept: undefined - undefined
Chapter:
SECTION - E
[3]31. (a) (i)

In angiosperms, the female gametophyte develops from a single cell of megasporangium.

Name that cell of megasporangium and describe the sequential changes it undergoes to form a mature female gametophyte.

Concept: undefined - undefined
Chapter:
[2]31. (a) (ii)

Describe the development of female gametophyte of angiosperms with the help of diagram.

Concept: undefined - undefined
Chapter:
OR
[1]31. (b) i.

Given below is situation related to birth control. Analyse the situation carefully and suggest appropriate contraceptive method that could be used. Also explain its mode of action.

Situation: To prevent entry of sperm into cervix.

Concept: undefined - undefined
Chapter:
[1]31. (b) ii.

Given below is situation related to birth control. Analyse the situation carefully and suggest appropriate contraceptive method that could be used. Also explain its mode of action.

Situation: Devices that are inserted by doctors or expert nurses in the vagina.

Concept: undefined - undefined
Chapter:
[1]31. (b) iii.

Given below is situation related to birth control. Analyse the situation carefully and suggest appropriate contraceptive method that could be used. Also explain its mode of action.

Situation: Effective emergency contraceptive.

Concept: undefined - undefined
Chapter:
[1]31. (b) iv.

Given below is situation related to birth control. Analyse the situation carefully and suggest appropriate contraceptive method that could be used. Also explain its mode of action.

Situation: Permanent method for male partner.

Concept: undefined - undefined
Chapter:
[1]31. (b) v.

Given below is situation related to birth control. Analyse the situation carefully and suggest appropriate contraceptive method that could be used. Also explain its mode of action.

Situation: Surgical method in female to prevent pregnancy.

Concept: undefined - undefined
Chapter:
[5]32. (a)
  1. Name the protozoan species that is responsible for causing the most serious and even fatal malerial disease.     [0.5]
  2. Name the host in which the parasite completes its sexual stages and explain the changes taking place.     [2]
  3. How does the parasite damage the human body after entering the blood stream?     [1.5]
  4. Suggest two effective preventive measures to control the spread of this disease in endemic regions.     [1]
Concept: undefined - undefined
Chapter:
OR
[5]32. (b)
[1]32. (b) (i)

What are biofertilizers?

Concept: undefined - undefined
Chapter:
[3]32. (b) (ii)

Name the different types of microorganisms used as bio-fertilizers in organic farming and explain how each contributes to soil fertility. 

Concept: undefined - undefined
Chapter:
[1]32. (b) (iii)

Write two advantages of using bio-fertilizers over chemical fertilizers.

Concept: undefined - undefined
Chapter:
[5]33. (a)
[2]33. (a) (i)

Watson and Crick’s discovery of double helical structure was based on which two findings. Also mention the name of the scientists associated with these findings.

Concept: undefined - undefined
Chapter:
[3]33. (a) (ii)

Write down the salient features of double helix structure of DNA.

Concept: undefined - undefined
Chapter:
OR
[5]33. (b)

Given below is a stretch of DNA showing the coding strand of structural gene of transcription unit.

5'- ATG ACC GTA TTT TCT GTA GTG CCC GTA CTT CAG GCA TTA 3'

  1. Write the corresponding template strand and m-RNA strand that will be transcribed along with its polarity.     [2]
  2. If GUA of transcribed mRNA is an intron, then depict the sequence involved in formation of mRNA/mature/processed hnRNA strand:
    1. In a bacterium     [1]
    2. In humans     [1]
  3. How many amino acids the resulting polypeptide will have after the process of translation in humans?     [1]
Concept: undefined - undefined
Chapter:

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