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Questions
Illustrate the following reaction giving suitable example in each case:Gabriel phthalimide synthesis
Write the reactions involved Gabriel phthalimide synthesis
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Solution 1
Solution 2
Gabriel Phthalimide Synthesis Used for the preparation of primary amine
Reactions involved in the preparation of primary amine from phthalimide are as follows:
Aromatic primary amines cannot be prepared by this process because aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.
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| Column I | Column II | ||
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\[\begin{array}{cc}
\ce{O}\phantom{.......................}\\
||\phantom{.......................}\\
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\end{array}\]
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