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Question
From their examination of the structure of DNA, What did Watson and Crick infer about the probable mechanism of DNA replication, coding capability, and mutation?
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Solution
Inference of Watson and Crick on DNA replication:
They concluded that each of the DNA strand in a helix act as template during DNA replication leading to formation of new daughter DNA molecules, which are complementary to parental strand, (i.e., Semi-conservative method of replication).
Inference on coding capability:
During transcription, the genetic information in the DNA strand is coded to mRNA as complementary bases, (except for uracil in place of thymine in RNA).
Inference on mutation:
Any changes in the nucleotide sequence of DNA leads to corresponding alteration in aminoacid sequence of specific protein thus confirming the validity of genetic code.
RELATED QUESTIONS
Explain replication of bacteriophage with the help of a suitable diagram.
Very Short Answer Question:
When does DNA replication takes place?
E. coli cell grown on 15N medium are transferred to 14N medium and allowed to grow for two generations. DNA extracted from these cells is ultracentrifuged in a cesium chloride density gradient. What density distribution of DNA would you expect in this experiment?
Which of the following statements is not true about DNA replication in eukaryotes?
Which of the following term correctly describes the movement of ribosome on the mRNA?
Which of the following is present at the sticky ends of a fragmented DNA molecule?
When the DNA molecule appears like inverted Y, it is ______
Match the following column.
| Column - I | Column - II |
| (A) DNA structure | 1. Muller and stadder |
| (B) Semiconservative replication of DNA | 2. Beadle and partum |
| (C) One gene-one enzyme theory | 3. Watson and crick |
| (D) Induction of mutation | 4. Massillon and stahl |
What background information did Watson and Crick had available with them for developing a model of DNA? What was their own contribution?
In prokaryotes, the primers of lagging strands are removed by ______.
