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Question
From their examination of the structure of DNA, What did Watson and Crick infer about the probable mechanism of DNA replication, coding capability, and mutation?
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Solution
Inference of Watson and Crick on DNA replication:
They concluded that each of the DNA strand in a helix act as template during DNA replication leading to formation of new daughter DNA molecules, which are complementary to parental strand, (i.e., Semi-conservative method of replication).
Inference on coding capability:
During transcription, the genetic information in the DNA strand is coded to mRNA as complementary bases, (except for uracil in place of thymine in RNA).
Inference on mutation:
Any changes in the nucleotide sequence of DNA leads to corresponding alteration in aminoacid sequence of specific protein thus confirming the validity of genetic code.
RELATED QUESTIONS
Explain replication of bacteriophage with the help of a suitable diagram.
As the base sequence present on one strand of DNA decides the base sequence of other strands; this strand is considered as ______.
Very Short Answer Question:
Why are Okazaki fragments formed on lagging strand only?
During DNA replication, Okazaki fragments are used to elongate ____________.
Read the following statements and select the correct option.
Statement I: DNA replication is continuous on leading strand while on the lagging strand it is discontinuous.
Statement II: DNA polymerase cannot initialize polymerization without a primer.
Match the following column.
| Column - I | Column - II |
| (A) DNA structure | 1. Muller and stadder |
| (B) Semiconservative replication of DNA | 2. Beadle and partum |
| (C) One gene-one enzyme theory | 3. Watson and crick |
| (D) Induction of mutation | 4. Massillon and stahl |
Okazaki is known for his contribution to the under tanding of:
During the replication of DNA, the separated strands are prevented from recoiling by using ______.
The nucleic acid synthesis takes place in ______.
In prokaryotes, the primers of lagging strands are removed by ______.
