मराठी

Differentiate between Leading stand and lagging strand.

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प्रश्न

Differentiate between Leading stand and lagging strand.

फरक स्पष्ट करा
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उत्तर

Feature Leading Strand Lagging Strand
1. Direction of synthesis Synthesized continuously in the same direction as the replication fork. Synthesized discontinuously in the opposite direction of the replication fork.
2. Formation Formed as a single, continuous strand. Formed in short fragments called Okazaki fragments.
3. Requirement of primers Requires only one RNA primer to start synthesis. Requires multiple RNA primers, one for each Okazaki fragment.
4. DNA polymerase movement Moves toward the replication fork. Moves away from the replication fork.
5. Speed of synthesis Faster because it is continuous. Slower because it is discontinuous.
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पाठ 5: Molecular Genetics - Evaluation [पृष्ठ ८५]

APPEARS IN

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संबंधित प्रश्‍न

What is the correct sequence of the stages in bacteriophage lytic cycle?

(A) Attachment, Penetration, Lysis, Multiplication

(B) Attachment, Penetration, Multiplication, Lysis

(C) Lysis, Penetration, Multiplication, Attachment

(D) Attachment, Lysis, Multiplication, Penetration


Explain replication of bacteriophage with the help of a suitable diagram.


Which enzyme does remove supercoils from replicating DNA?


Long Answer Question:

Explain the process of DNA replication.


A DNA segment has 75 cytosine and 40 thymine nucleotides. What shall be the total number of phosphates in the DNA segment?


Define Heterochromatin.


How Meselson and Stahl explained the concept of Semiconservative Replication of DNA experimentally?


Which of the following statements about DNA replication is not correct?


During DNA replication, Okazaki fragments are used to elongate ____________.


Enzyme ______ brings about the DNA unwinding by breaking weak hydrogen bonds in the vicinity of origin.


Identify the CORRECT combination of statements with respect to DNA synthesis.

I. Always the direction of DNA polymerization 5' → 3' when referring to the polarity of strand being synthesized.

II. DNA ligase forms hydrogen bonds between two newly synthesized DNA strands.

III. DNA polymerases on their own cannot initiate the process of replication.

IV. DNA polymerase can catalyse polymerization in both 5'→ 3' and 3'→ 5' direction.


Which of the following is the function of single-strand binding proteins?


______ carbon atoms of successive nucleotides of nucleic acid are linked by Phospho-diester bond.


Match the following column.

Column - I Column - II
(A) DNA structure 1. Muller and stadder
(B) Semiconservative replication of DNA 2. Beadle and partum
(C) One gene-one enzyme theory 3. Watson and crick
(D) Induction of mutation 4. Massillon and stahl

During replication of DNA Okazaki fragments are formed in the direction:


Okazaki segments are formed during ______.


What background information did Watson and Crick had available with them for developing a model of DNA? What was their own contribution?


Select the incorrect statement regarding DNA replication.


Draw a suitable diagram of replication of eukaryotic DNA and label any three parts.


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