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ISC (Science) ISC Class 12 - CISCE Important Questions

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In a karyotype analysis, X and Y chromosomes represent sex chromosomes.

Name the scientist who discovered the X chromosome.

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Chapter: [5] Principles of Inheritance and Variation
Concept: Chromosomal Theory of Inheritance

Jacob is genetically a carrier of the disorder that affects the shape of the RBCs, as shown in the diagram below. His son James suffers from the same disorder.

  1. Give the biochemical reason for the disorder that changes the shape of the RBCs, as shown above.
  2. Draw a Punnett square to show the genotype of the mother of James.
  3. Name and define the type of 'point mutation' responsible for this disorder.
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Chapter: [5] Principles of Inheritance and Variation
Concept: Human Genetic Disorders

Consider the following information and answer the question that follows:

  • Reshma’s mother is normal, but her father is suffering from PKU.
  • Reshma is suffering from PKU. She has two younger brothers who are identical twins; both are suffering from PKU. Reshma’s two elder sisters are normal.
  • Reshma marries Robert, who is normal. Reshma gives birth to a son named Jason who is normal. After some time, Reshma and Robert have two more children: a daughter with symptoms of PKU and a son without any symptoms of PKU.

Make a single pedigree chart using the above information to show the pattern of inheritance of phenylketonuria (PKU) in the family of Reshma.

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Chapter: [5] Principles of Inheritance and Variation
Concept: Chromosomal Theory of Inheritance

What are introns?

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Chapter: [6] Molecular Basis of Inheritance
Concept: Transcription

Transcription is the transfer of genetic code from a DNA molecule to ______.

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Chapter: [6] Molecular Basis of Inheritance
Concept: Transcription

Initiation codon of protein synthesis in Eukaryotes is ______.

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Chapter: [6] Molecular Basis of Inheritance
Concept: Transcription

Give one significant contribution to the following scientists:

Sanger

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Chapter: [6] Molecular Basis of Inheritance
Concept: Human Genome Project

What is the central dogma?

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Chapter: [6] Molecular Basis of Inheritance
Concept: Transcription

Explain the mechanism of transcription in a prokaryotic cell.

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Chapter: [6] Molecular Basis of Inheritance
Concept: Transcription

Give four adaptations in flowers pollinated by insects.

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Adaptive Radiation

Name and define the three types of natural selection.

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Darwin’s Theory of Natural Selection (Darwinism)

The largest unit in which gene flow is possible is :

(1) Organism

(2) Population

(3) Species

(4) Genes

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Darwin’s Theory of Natural Selection (Darwinism)

State Hardy-Weinberg’s principle.

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle

Differentiate between Directional natural selection and Disruptive natural selection. 

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle

Explain the evolution of the long neck of giraffe according to Charles Darwin. 

Appears in 1 question paper
Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Darwin’s Theory of Natural Selection (Darwinism)

What is the Founder's effect?

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle

Give a mathematical expression for Hardy Weinberg's principle.

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Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle

A population of 200 fruit flies is in Hardy Weinberg equilibrium. The frequency of the allele (a) 0.4. Calculate the following:

Frequency of the allele (A).

Appears in 1 question paper
Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle

A population of 200 fruit flies is in Hardy Weinberg equilibrium. The frequency of the allele (a) 0.4. Calculate the following:

The number of homozygous dominant fruit flies.

Appears in 1 question paper
Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle

A population of 200 fruit flies is in Hardy Weinberg equilibrium. The frequency of the allele (a) 0.4. Calculate the following:

The number of homozygous recessive fruit flies.

Appears in 1 question paper
Chapter: [8] Evidences and Theories of Biological Evolution
Concept: Hardy Weinberg’s Principle
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