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Describe the various steps of Griffith’s experiment that led to the conclusion of the 'Transforming Principle'.
Concept: Properties of Genetic Material
How did the chemical nature of the ‘Transforming Principle' get established?
Concept: Properties of Genetic Material
Answer the following question.
Construct and label a transcription unit from which the RNA segment given below has been transcribed. Write the complete name of the enzyme that transcribed this RNA.

Concept: Protein Synthesis >> Process of Transcription in Bacteria
Write the contributions of the following scientists in deciphering the genetic code.
George Gamow; Hargobind Khorana; Marshall Nirenberg; Severo Ochoa
Concept: Genetic Code
Answer the following question.
State the importance of a Genetic code in protein biosynthesis.
Concept: Genetic Code
Explain the process of aminoacylation of tRNA and its role in the process of translation.
Concept: Protein Synthesis >> Translation
Mention the evolutionary significance of the Homo erectus
Concept: Evolution of Life Forms - a Theory
At which stage during evolution did human use hides to protect their bodies and buried their dead?
Concept: Human Evolution
Why is secondary immune response more intense than the primary immune response in humans?
Concept: Immunity
Answer the following question:
The principle of vaccination is based on the property of the "memory" of the immune system. Taking one suitable example, justify the statement.
Concept: Immunity
Answer the following question.
Differentiate between the roles of B-lymphocytes and T-lymphocytes in generating immune responses.
Concept: Immunity
Why is a malignant tumour considered to be more damaging than a benign tumour? Explain.
Concept: Cancer
Name the type of association that the genus Glomus exhibits with higher plants.
Concept: Microbes as Biocontrol Agents
Explain the process of sewage water treatment before it can be discharged into natural water bodies.
Concept: Microbes in Sewage Treatment
Answer the following question:
Why does 'Swiss Cheese' develop large holes?
Concept: Microbes in Household Products
How does a gene therapy involving direct modification of the cells, in order to achieve a therapeutic goal is used in the treatment of ADA deficiency? Explain.
Concept: Applications of Biotechnology in Health and Medicine
A host cell must be made competent, before it is able to receive an rDNA. Justify.
Concept: Applications of Biotechnology in Health and Medicine
- Give an example of a genus of virus used as narrow spectrum insecticidal biocontrol agent.
- How does its use serve as an aid in overall integrated pest management programme?
Concept: Microbes as Biocontrol Agents
Why must a cell be made ‘competent’ in biotechnology experiments? How does calcium ion help in doing so?
Concept: Tools of Recombinant DNA Technology >> Competent Host (For Transformation with Recombinant DNA)
Explain with the help of a suitable example the naming of a restriction endonuclease.
Concept: Tools of Recombinant DNA Technology >> Restriction Enzymes
