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The first codon to be deciphered was ______ which codes for ______.

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Question

The first codon to be deciphered was ______ which codes for ______.

Options

  • AAA, proline

  • GGG, alanine

  • UUU, Phenylalanine

  • TTT, arginine

MCQ
Fill in the Blanks
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Solution

The first codon to be deciphered was UUU which codes for Phenylalanine.

Explanation:

In 1961, Marshall Nirenberg and Heinrich Matthaei performed a groundbreaking experiment to begin “cracking” the genetic code. They used a synthetic poly-U RNA strand (made entirely of Uracil bases) in a cell-free system. They discovered that this UUU message led to the creation of a protein chain consisting solely of the amino acid phenylalanine. This was the first time a specific codon was successfully matched to a specific amino acid, marking a massive milestone in molecular biology.
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Chapter 5: Molecular Genetics - Evaluation [Page 85]

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