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Question
Which moieties of nucleosides are involved in the formation of phosphodiester linkages present in dinucleotides? What does the word diester in the name of linkage indicate? Which acid is involved in the formation of this linkage?
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Solution
When nucleoside is linked to phosphoric acid at 5-position of sugar moiety, it forms a nucleotide. Nucleotides are joined together by phosphodiester link between 5' and 3' carbon atoms of the pentose sugar.
Phosphoric acid is involved in the formation of this linkage.
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