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Question
If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male progeny, the disease is ______.
Options
Sex-linked recessive
Autosomal dominant
Sex-linked dominant
Autosomal recessive
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Solution
If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male progeny, the disease is sex-linked recessive.
Explanation:
If a genetic disease is passed from a phenotypically normal but carrier female to only some of the male offspring, it indicates a sex-linked recessive inheritance. In such cases, females can be carriers without showing symptoms because they have two X chromosomes, and the defective gene is recessive. Males, having only one X chromosome, exhibit the disease if they inherit the affected X from the carrier mother, leading to the disease manifesting only in some of the male progeny. This pattern is typical for diseases like haemophilia and color blindness.
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RELATED QUESTIONS
Why are thalassemia and haemophilia categorized as Mendelian disorders? Write the symptoms of these diseases. Explain their pattern of inheritance in humans.
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Match the Column-I with Column-II and choose the CORRECT answer
| Column-I | Column-II | ||
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