Advertisements
Advertisements
Questions
Identify chromosomal disorder caused due to non-disjunction of the 21st number of chromosomes and enlist its symptoms.
Identify chromosomal disorder caused due to non-disjunction of 21% chromosome and enlist its characteristics.
Advertisements
Solution
Down syndrome is usually caused by an error in cell division called non-disjunction. Non-disjunction results in an embryo with three copies of chromosome 21 instead of the usual two.
Common Symptoms (Characteristics) of Down syndrome are:
- Mild or moderate mental retardation and poor skeletal development.
- Distinct facial features like small head, ears and mouth.
- Eyes slant up and out with internal epicanthal folds.
RELATED QUESTIONS
What will be the phenotype of progeny, if a carrier haemophilic female marries a normal male?
Give an example of a human disorder that is caused due to a single gene mutation.
Very Short Answer Question.
Give an example of a chromosomal disorder caused due to nondisjunction of autosomes.
In human beings 45 chromosomes/single X/XO abnormality causes ______.
Read the following statements and select the correct option.
i. Genetic disorders are broadly categorised as, Mendelian disorders and chromosomal disorders.
ii. Mendelian disorders are caused due to absence or excess of one or more chromosomes or their abnormal arrangement.
iii. Chromosomal disorders are mainly caused due to alteration or mutation in the gene.
If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male progeny, the disease is ______.
Females with Turner’s syndrome have ______.
It is said, that the harmful alleles get eliminated from population over a period of time, yet sickle cell anaemia is persisting in human population. Why?
Lipoprotein lipase deficiency (LPLD)is a genetic disorder in which a person has a defective gene for lipase. This leads to high triglycerides, stomach pain, and fat deposits under the skin. It may eventually affect the liver, pancreas and may also cause diabetes. The disorder occurs if a child acquires defective genes from both parents (autosomal recessive). ERT (enzyme replacement treatment) is one of the treatments offered to patients with LPLD.
-
- What procedure is followed in ERT?
- What could be one possible drawback of ERT?
- How can LPLD be treated using Biotechnology? Elaborate.
Give the genotype of Klinefelter’s syndrome.
