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Question
In human beings 45 chromosomes/single X/XO abnormality causes ______.
Options
Down's syndrome
Klinfelter's syndrome
Turner's syndrome
Edward's syndrome
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Solution
In human beings 45 chromosomes/single X/XO abnormality causes Turner's syndrome.
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Turner's syndrome is an example of monosomy. It is formed by the union of an allosome-free egg and a normal 'X' containing sperm or a normal egg and an allosome-free sperm. The individual has 2n = 45 chromosomes (44 + X0) instead of 46. Such individuals are sterile females who have rudimentary ovaries, underdeveloped breasts, small uterus, short stature, webbed neck, and abnormal intelligence. They may not menstruate or ovulate. This disorder can be treated by giving female sex hormones to women from the age of puberty to make them develop breasts and have menstruation. This makes them feel more normal.
Turner's syndrome is an example of ______
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