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Give an example of a human disorder that is caused due to a single gene mutation.

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Question

Give an example of a human disorder that is caused due to a single gene mutation.

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Solution

Sickle-cell anaemia is a human genetic disorder caused by a single gene mutation. In sickle-cell anaemia, glutamic acid (Glu) at the 6th position of beta globin chain (of haemoglobin molecule) is replaced by valine (Val).

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Chapter 4: Principles of Inheritance and Variation - Test Your Progress [Page 205]

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Nootan Biology [English] Class 12 ISC
Chapter 4 Principles of Inheritance and Variation
Test Your Progress | Q 80. | Page 205
Nootan Biology [English] Class 12 ISC
Chapter 4 Principles of Inheritance and Variation
Test Your Progress | Q 105. | Page 206
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