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प्रश्न
Give an example of a human disorder that is caused due to a single gene mutation.
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उत्तर
Sickle-cell anaemia is a human genetic disorder caused by a single gene mutation. In sickle-cell anaemia, glutamic acid (Glu) at the 6th position of beta globin chain (of haemoglobin molecule) is replaced by valine (Val).
संबंधित प्रश्न
The genotype of a person withTumer's syndrome will be:
(i) 44+XXY
(ii) 44+XYY
(iii) 44+XO
(iv) 44+XXYY
State any two symptoms of Down’s syndrome.
Attempt any TWO of the following:
‘The gene for sickle cell anaemia in homozygous condition is lethal and produces sickle cell trait in heterozygous carrier’. Explain.
Which of the following traits is never observed in a human female?
What is the reason for the 21st trisomy?
Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement.
The person with Turner’s syndrome has ______.
Trisomy is represented by ______.
Rajesh and Mahesh have defective haemoglobin due to genetic disorders. Rajesh has too few globin molecules while Mahesh has incorrectly functioning globin molecules. Identify the disorder they are suffering from.
| Rajesh | Mahesh | |
| A. | Sickle cell anaemia - an autosome linked recessive trait | Thalassemia - an autosome linked dominant trait |
| B. | Thalassemia - an autosome linked recessive blood disorder | Sickle cell anaemia - an autosome linked recessive trait |
| C. | Sickle cell anemia - an autosome linked recessive trait | Thalassemia - an autosome linked recessive blood disorder |
| D. | Thalassemia - an autosome linked recessive blood disorder | Sickle cell anaemia - an autosome linked dominant trait |
Short stature in females, webbed neck absence of menstrual cycle and sterility are characteristics which of the following disease?
