Advertisements
Advertisements
प्रश्न
Give an example of a human disorder that is caused due to a single gene mutation.
Advertisements
उत्तर
Sickle-cell anaemia is a human genetic disorder caused by a single gene mutation. In sickle-cell anaemia, glutamic acid (Glu) at the 6th position of beta globin chain (of haemoglobin molecule) is replaced by valine (Val).
संबंधित प्रश्न
Why are thalassemia and haemophilia categorized as Mendelian disorders? Write the symptoms of these diseases. Explain their pattern of inheritance in humans.
During a medical investigation, an infant was found to possess an extra chromosome 21. Describe the symptoms the child is likely to develop later in the life.
In human beings 45 chromosomes/single X/XO abnormality causes ______.
Identify the characteristics that are observed in an individual suffering from Klinefelter syndrome.
i. Gynaecomastia, under developed testis and no spermatogenesis.
ii. Voice pitch is harsh.
iii. They are tall with long arms.
In Klinefelter syndrome, an extra chromosome is a result of non-disjunction of X-chromosome during ____________.
In sickle-cell anaemia, shape of RBCs under oxygen tension becomes ______.
Where are the genes for cytoplasmic male sterility in plants located?
Mongolism is a genetic disorder which is caused by the presence of an extra chromosome number ______.
Read the following and answer from given below:
Turner's syndrome is an example of monosomy. It is formed by the union of an allosome-free egg and a normal 'X' containing sperm or a normal egg and an allosome-free sperm. The individual has 2n = 45 chromosomes (44 + X0) instead of 46. Such individuals are sterile females who have rudimentary ovaries, underdeveloped breasts, small uterus, short stature, webbed neck, and abnormal intelligence. They may not menstruate or ovulate. This disorder can be treated by giving female sex hormones to women from the age of puberty to make them develop breasts and have menstruation. This makes them feel more normal.
Turner's syndrome is an example of ______
Describe Turner's syndrome.
