Advertisements
Advertisements
प्रश्न
Give an example of a human disorder that is caused due to a single gene mutation.
Advertisements
उत्तर
Sickle-cell anaemia is a human genetic disorder caused by a single gene mutation. In sickle-cell anaemia, glutamic acid (Glu) at the 6th position of beta globin chain (of haemoglobin molecule) is replaced by valine (Val).
संबंधित प्रश्न
What do sex linked traits appear in males than in females?
Identify the INCORRECT statement.
Identify I and II in the given diagram of chromosome.
In sickle cell anaemia glutamic acid is replaced by valine. Which one of the following triplets codes for valine?
Genes for cytoplasmic male sterility in plants are generally located in ______.
Mental retardation in man associated with sex chromosomal abnormality is usually due to ______.
Failure of segregation of chromatids during cell division results in the gain or loss of chromosomes, this is called as ______.
Rajesh and Mahesh have defective haemoglobin due to genetic disorders. Rajesh has too few globin molecules while Mahesh has incorrectly functioning globin molecules. Identify the disorder they are suffering from.
| Rajesh | Mahesh | |
| A. | Sickle cell anaemia - an autosome linked recessive trait | Thalassemia - an autosome linked dominant trait |
| B. | Thalassemia - an autosome linked recessive blood disorder | Sickle cell anaemia - an autosome linked recessive trait |
| C. | Sickle cell anemia - an autosome linked recessive trait | Thalassemia - an autosome linked recessive blood disorder |
| D. | Thalassemia - an autosome linked recessive blood disorder | Sickle cell anaemia - an autosome linked dominant trait |
Trisomy of 21st chromosome leads to a disorder ______.
At what level does the defect occur in chromosomal disorders?
