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Questions
Define ‘genomics’. Give any ‘two’ applications of it.
Define Genomics. Give any two applications of the genomics.
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Solution 1
Genomics is the study of the molecular organization of the genome. Human genome project (HGP) is aimed to produce the map of human genome. These maps help in the understanding location of genes, functions, distance between different genes and nucleotide sequence of each gene. HGP reveals that 99.9 % of genes are same in all individuals and only 0.001% difference is seen in DNA. Biotechnological applications for human health – Insulin is a hormone which regulates blood glucose level. In Diabetes mellitus patients, due to hyposecretion of insulin by pancreas, blood sugar level increases. Insulin is produced by using biotechnological methods. Vaccines are antigenic preparation which stimulates production of antibodies and induce immunity against several diseases.
Solution 2
Definition:
Genomics is the study of genomes through analysis, sequencing, and mapping of genes along with the study of their functions.
Applications of Genomics:
- Structural and functional genomics is used for different purposes in the improvement of crop plants, human health, and livestock.
- The knowledge and understanding acquired from genomics research can be applied in a number of different sectors, including medicine, biotechnology, and social sciences.
- It helps in the treatment of genetic disorders through gene therapy.
- Genomics is used in agriculture to develop transgenic crops having more desirable characters.
- Genetic markers developed in genomics, have applications in forensic analysis.
- Genomics can lead to introducing new genes in microbes to produce enzymes, therapeutic proteins, and even biofuels.
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RELATED QUESTIONS
What does abbreviation HGP stand for?
Answer the following question.
List the two methodologies which were involved in the human genome project. Mention how they were used.
Identify the main aims of Human Genome Project.
I. Taking care of the legal, ethical and social issues which may arise from the project.
II. Transfer of the related technologies to the private sectors, such as industries.
III. To develop tools and techniques for analysis of the data.
IV. To store the information collected from the project in databases.
V. Mapping the entire human genome at the level of nucleotide sequences.
In which of the following year the Human Genome Project (HGP) was initiated?
Of a normal couple, half the sons are haemophilic while half the daughters are carriers. The gene is located on ______.
Genes located on Y-chromosome are ______.
Estimated number of genes in human beings is ______.
The total number of genes in humans is far less (< 25,000) than the previous estimate (upto 1,40,000 gene). Comment.
Give an account of the methods used in sequencing the human genome.
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