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प्रश्न
Illustrate using any one example of transgenic bacteria.
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उत्तर
Genetic technology has prepared human insulin. Insulin is made up of two small polypeptide chains, chain ‘A’ and chain ‘B’ which are linked to each other by disulphide bonds. In human insulin, a pro-hormone is synthesised which contains C peptide. Mature insulin does not contain this peptide ‘C’; it separates from insulin during the maturation process. In 1983, scientists created two DNA sequences for the ‘A’ and ‘B’ chains of human insulin and put them into E. coli to make these insulin chains. We removed these separately produced chains ‘A’ and ‘B’ and joined them to each other by disulphide bonds to prepare human insulin. Insulin is a useful medicine for controlling diabetes. The credit for cloning the insulin gene goes to Dr. Saran Narang of Indian origin. He conducted his experiment in Ottawa, Canada.
संबंधित प्रश्न
Why do children cured by enzyme-replacement therapy adenosine deaminase deficiency need periodic treatment?
Expand the Given and mention one application of each:
PCR
What is gene therapy? Illustrate using the example of adenosine deaminase (ADA) deficiency.
What is gene therapy? Name the first clinical case in which it was used.
Answer the following question.
Explain the various steps involved in the production of artificial insulin.
Describe the role of high temperature.
What are recombinant vaccines? Explain the types.
Explain how recombinant Insulin can be produced.
A probe which is a molecule used to locale-specific sequences in a mixture of DNA or RNA Mole cubs could be ______.
The site of production of ADA the body is ______.
Which is false about antibiotics?
ELISA is based on:
Which of the following is the correct sequence of steps in a PCR (Polymerase Chain Reaction)?
The Adenosine deaminase deficiency results in ______.
Can a disease be detected before its symptoms appear? Explain the principle involved.
Define Antigen and Antibody. Name any two diagnostic kits based upon them.
How is a mature, functional insulin hormone different from its prohormone form?
List the disadvantages of insulin obtained from the pancreas of slaughtered cows and pigs:
The ______ gene from Bacillus thuringiensis produces a protein that forms crystalline inclusions in bacterial spores.
Choose the INCORRECT statement.
