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प्रश्न
List the disadvantages of insulin obtained from the pancreas of slaughtered cows and pigs:
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उत्तर
- Insulin being a hormone is produced in very little amounts in the body. Hence, a large number of animals need to be sacrificed for obtaining small quantities of insulin. This makes the cost of insulin very high. [Demand being many fold higher than supply].
- Slaughtering of animals is also not ethical.
- There is potential of immune response in humans against the administered insulin which is derived from animals.
- There is possibility of slaughtered animals being infested with some infectious microorganism which may contaminate insulin.
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संबंधित प्रश्न
State the role of C-peptide in human insulin.
Explain how insulin can be produced using recombinant DNA technology.
Give a schematic representation of the transformation of a pro-insulin into insulin.
Answer the following question.
Describe the roles of heat, primers, and the bacterium Thermus aquaticus in the process of PCR.
Explain how recombinant Insulin can be produced.
A patient suffering from diabetes mellitus will have ______.
Which of the following is a neuropeptide hormone?
Human insulin is being commercially produced form a transgenic species of ______.
Choose the correct option regarding retrovirus.
Now a days it is possible to detect the mutated gene causing cancer by allowing a radioactive probe to hybridize its complimentary DNA in a clone of cells, followed by its detection using autoradiography because ______
Give the full form of ELISA. Which disease can be detected using it? Discuss the principle underlying the test.
Eli Lilly's contribution for diabetic patients through r-DNA technology has been overwhelmingly accepted. Explain how?
The diagram given below represents the schematic structure of proinsulin, which undergoes certain modifications before it becomes a fully functional insulin.
Study the diagram carefully and answer the questions that follow:
- State the change the proinsulin undergoes to become fully functional.
- Name the modern scientific technique used for the production of human insulin.
- How are the two polypeptide chains of the fully functional insulin held together?
How many cycles of PCR are required to produce 250 molecules of DNA, starting with a single parental strand?
The ______ gene from Bacillus thuringiensis produces a protein that forms crystalline inclusions in bacterial spores.
In the recombinant production of humulin using Escherichia coli, which plasmid vector and bacterial gene are fused with the human insulin A and B chain sequences?
Which of the following describes the final step in the laboratory synthesis of biologically active humulin from isolated chains?
The first edible vaccine was developed in tobacco plants to express which specific antigen?
Severe Combined Immunodeficiency Disease (SCID) caused by adenosine deaminase (ADA) deficiency arises due to which pathological mechanism?
