The special groups of hormone-secreting cells scattered in the pancreas that produce insulin, glucagon, and other hormones for blood sugar regulation are called Islets of Langerhans.
Definitions [37]
Definition: Response
A response is the reaction or change in an organism produced as a result of a stimulus.
Definition: Stimulus
A stimulus is any sudden change in the internal or external environment that brings about a response in an organism.
Definition: Neuron (Nerve Cell)
A neuron is a specialised cell that forms the structural and functional unit of the nervous system and is responsible for transmitting nerve impulses.
Definition: Effectors
Effectors are muscles or glands that produce a response by contracting or secreting substances when stimulated by nerve impulses.
Define the following term:
Synaptic cleft
Axon terminals are closely placed near the dendrites of another one or more neurons but are not connected. Such gaps in between are called synaptic clefts.
Definition: Receptors
Receptors are specialised sensory cells that receive stimuli and convert them into nerve impulses.
Definition: Nerve Impulse
A nerve impulse is an electrical disturbance that travels along a neuron in response to a stimulus.
Definition: Synaptic Cleft
Axon terminals are closely placed near the dendrites of another one or more neurons but are not connected. Such gaps in between are called synaptic clefts.
Define the following term:
Nerve
A nerve is a bundle of axons from numerous neurons encased in a protective sheath.
Definition: Nodes of Ranvier
Nodes of Ranvier are gaps present at intervals in the myelin sheath that help in faster transmission of nerve impulses.
Definition: Neurolemma (Neurilemma)
Neurolemma is the outermost thin protective sheath covering the myelin sheath of a nerve fibre.
Define the following:
Neuron
Neurons are the building blocks of the nervous system and transmit information throughout the body.
Define the following:
Reflex arc
The path that an impulse takes in a reflex action is called a reflex arc.
Define the following:
Motor neuron:
The neurons which carry impulses from the brain or spinal cord to the body parts are called motor or efferent neurons.
Define the term:
Sensory neuron
The neurons which carry impulses from the body parts to the spinal cord or the brain are called sensory or afferent neurons. For example, the optic nerve of the eye.
Define stimulus.
A stimulus is an agent or a sudden change in the external or internal environment that changes an organism or body parts. e.g., light, sound, heat, pain, hunger.
Definition: Meninges
The brain is protected by 3 membranous coverings called meninges (meninx: membrane) which continue backwards on the spinal cord.
Definition: Meningitis
Inflammation of the meninges is called meningitis.
Define the following term:
Adaptation
Adaptation is the process by which the human eye adjusts to changes in light intensity.
- Light Adaptation: When a person moves from a dark environment to a brightly lit area (e.g., stepping out of a cinema hall in the afternoon), they initially experience a dazzling effect. After a few seconds, the eyes adjust to the brightness. This process is called light adaptation.
- Dark Adaptation: When a person enters a dark area from a brightly lit environment (e.g., entering a cinema hall), they initially struggle to see clearly. Gradually, their vision improves as the eyes adapt to the darkness. This process is called dark adaptation.
Define the following term:
Ear ossicles
The middle ear contains three tiny bones malleus, incus and stapes or hammer, anvil and stirrup in popular terms and a eustachian tube which connects the cavity of the middle ear with the throat. The three bones are collectively called the ear ossicles ( osseus: bone, ossicle : little bone).
Define the following term:
Hormones
Hormones are chemical messengers created by the endocrine glands and transported through the bloodstream to govern body functions such as development, metabolism, reproduction and mood by interacting with specific target cells.
Definition: Endocrine System
A group of glands and glandular cells that secrete hormones to regulate and coordinate various functions in the body through chemical control.
Define the following term:
Endocrine system
The endocrine system is defined as a group of organs performing an overall common function. The endocrine glands secrete certain chemicals called hormones.
Define the following:
Hormone
Hormone is a molecule that is created and secreted in very minute quantities into the blood stream by an endocrine gland or a specialized nerve cell that governs the growth or functioning of a specific tissue organ in a distant area of the body, e.g., insulin
Define the following term:
Myxoedema
Myxoedema is a condition that affects an adult if his thyroid does not function properly; in this condition, the person becomes sluggish with swelling of the face and hands.
Define the following:
Mineralization
It is the process by which some microbes decompose humus to release inorganic nutrients.
Definition: Islets of Langerhans
Define the following:
Exocrine gland
- Glands that discharge secretions into ducts are known as exocrine glands.
- Sebaceous glands in the skin, salivary glands in the buccal cavity, etc. are examples of exocrine glands.
Definition: Synapse
Synapse (syn: together, apse: gap/window) is the point of contact between the terminal branches of the axon of a neuron with the dendrites of another neuron separated by a fine gap.
or
The junction between two nerve cells having a minute gap called synaptic cleft through which nerve impulse is transmitted by neurotransmitters is called synapse.
Definition: Sodium Pump
The sodium pump is a cellular mechanism that uses energy from ATP to actively transport sodium ions out of the axon, helping restore the resting state after depolarisation.
Definition: Polarised State
The polarised state is when the outer side of a nerve fibre carries a positive charge due to more Na⁺ ions outside the axon membrane in the resting condition.
Definition: Reflex Action
It is an automatic/quick/immediate, involuntary action in the body brought about by a stimulus.
Define the following:
Reflex action
Reflex action is an automatic/quick/immediate, involuntary action in the body brought about by a stimulus. This mechanism prevents injury to the body by triggering a rapid and automatic response.
Definition: Synaptic Cleft
The small intercellular space of about 20–30 nm present between presynaptic and postsynaptic neurons is called synaptic cleft.
Definition: Synaptic Transmission
The process by which a nerve impulse is conducted from the presynaptic neuron to the postsynaptic neuron by neurotransmitters is called synaptic transmission.
Definition: Electrical Synapse
The type of synapse in which transmission of impulse occurs directly through a narrow gap by electrical current is called electrical synapse.
Definition: Chemical Synapse
The type of synapse in which transmission of impulse occurs through chemical neurotransmitters across a wider synaptic gap is called chemical synapse.
Key Points
Key Points: Neuron
Key Points: Human Nervous System
Key Points: Different regions of Brain and its functions:
| Part | Description | Location | Structure | Main Functions |
|---|---|---|---|---|
| Cerebrum | Largest part of the brain, also called the large brain | Upper part of cranial cavity | Two hemispheres with many convolutions | Voluntary actions; intelligence, memory, thinking, decision-making |
| Cerebellum | Smaller part of brain situated below cerebrum | Back of cranial cavity | Shallow grooves on surface | Coordination of movements; body balance |
| Medulla Oblongata | Hindmost part of brain connecting brain to spinal cord | Lower brainstem | Pyramidal structures; continuous with spinal cord | Controls breathing, heartbeat, swallowing, coughing |
| Spinal Cord | Long cylindrical part of CNS extending from medulla | Vertebral column | Ends as filum terminale | Reflex actions; conduction of impulses to and from brain |
Key Points: Human Brain
Key Points: Spinal Cord
Key Points: Types of PNS
| Type | Cranial Nerves | Spinal Nerves |
| Origin | Directly from the brain. | From the spinal cord. |
| Function | Connect the brain to the head, neck, thorax, and abdomen; manage motor control, sensory perception, and digestion. | Link the spinal cord to limbs, skin, and other body parts; transmit sensory information and motor commands. |
| Number | 12 pairs | 31 pairs |
| Region | Head, thorax, abdomen | Various spinal regions |
|
Examples/ Details |
Optic nerve (2): Vision. Vagus nerve (10): heart rate, digestion, and breathing. |
Cervical (8 pairs): neck, shoulders, arms. Thoracic (12 pairs): chest, abdominal muscles. Lumbar/Sacral (10 pairs): legs, pelvis, lower back. Coccygeal (1 pair): Tailbone. |
Key Points: Human Eye
- The human eye works like a camera, forming a real and inverted image on the retina, which is light-sensitive.
- The cornea allows light to enter the eye and performs most of the refraction, while the lens fine‑tunes the focus.
- The iris controls the pupil, regulating the amount of light entering the eye—contracting in bright light and widening in dim light.
- The power of accommodation is the ability of the eye lens to change its focal length by altering its curvature using the ciliary muscles.
- For a normal eye, the near point is 25 cm and the far point is at infinity.
Key Points: Human Ear
- The ear has three main parts: outer ear, middle ear, and inner ear.
- The outer ear includes the pinna and auditory canal, ending at the eardrum (tympanum).
- The middle ear contains three tiny bones — malleus (hammer), incus (anvil), and stapes (stirrup) — called ossicles, and is connected to the throat by the eustachian tube.
- The stirrup fits on the oval window, and a second membrane-covered opening called the round window separates the middle ear from the inner ear.
- The inner ear includes the cochlea (with the organ of Corti for hearing) and the semicircular canals for dynamic balance.
- The vestibule (utriculus and sacculus) contains sensory cells responsible for static balance when the body is stationary.
Key Points: Pituitary Gland
Key Points: Thyroid Gland
1. The thyroid gland is a butterfly-shaped gland located in the neck and secretes thyroxine and calcitonin.
2. Thyroxine controls basal metabolic rate, influences growth, mental development, bone formation, and body temperature.
3. Hypothyroidism may cause:
- Simple goitre (due to iodine deficiency),
- Cretinism (dwarfism and mental retardation in children),
- Myxoedema (sluggishness and swelling in adults).
4. Hyperthyroidism leads to exophthalmic goitre with symptoms like protruding eyes, neck swelling, high metabolism, rapid heartbeat, and breathlessness.
5. Use of iodised salt helps prevent thyroid-related issues caused by iodine deficiency.
Key Points: Adrenal Glands
Key Points: Pancreas
- Pancreas functions both as an exocrine gland (secreting pancreatic juice into the duodenum) and an endocrine gland (secreting hormones into the blood).
- The Islets of Langerhans contain beta cells (secrete insulin) and alpha cells (secrete glucagon), which regulate blood sugar levels.
- Insulin lowers blood glucose by promoting glucose uptake by cells and storing excess glucose as glycogen in the liver and muscles.
- Under-secretion of insulin causes diabetes mellitus (hyperglycemia), with symptoms like excessive urination, thirst, weakness, and sugar in urine.
- Glucagon raises blood sugar by converting glycogen to glucose in the liver; overdose of insulin can lead to hypoglycemia or insulin shock.
Key Points: Reflex Action
- Voluntary actions are performed consciously, while involuntary actions (reflexes) occur automatically without conscious control.
- A stimulus is any change in the environment that initiates a reflex action.
- Reflex actions are quick, automatic responses to stimuli and do not require conscious thought.
- Examples of reflexes include withdrawal of hand from a hot object, shivering in cold, and sweating in heat.
- All reflexes are triggered by sensory stimulation and result in either muscular movement or glandular secretion.
Key Points: Disorders of nervous system
| Disorder | Cause | Major Symptoms | Key Points |
|---|---|---|---|
| Psychological Disorders | Disturbance in mood, thinking, or behaviour | Anxiety, depression, stress, poor attention, abnormal behaviour | Includes ID, ASD, BD, depression, anxiety, ADHD; affects daily life |
| Parkinson’s Disease | Degeneration of dopamine-producing neurons in CNS | Tremors, muscle stiffness, difficulty in walking, poor coordination | Symptoms develop gradually; movement disorder |
| Alzheimer’s Disease | Loss of cholinergic neurons and amyloid protein accumulation | Memory loss, impaired thinking, reasoning, and behaviour | Most common dementia; age-related; no cure but progression can be slowed |
Key Points: Generation of nerve impulse
| Aspect | Depolarization | Repolarization |
|---|---|---|
| Meaning | Change in membrane polarity from resting to active state | Restoration of membrane polarity to resting state |
| Na⁺ channel status | Voltage-gated Na⁺ channels open | Na⁺ channels close and become inactive |
| K⁺ channel status | K⁺ channels remain closed | Voltage-gated K⁺ channels open |
| Ion movement | Rapid influx of Na⁺ into the axon | Rapid efflux of K⁺ out of the axon |
| Membrane potential | Rises from –70 mV to +30 to +60 mV | Falls back towards –70 mV |
| Electrical charge | Inner surface becomes positive | Inner surface becomes negative |
| Nature of process | Initiates action potential | Terminates action potential |
| Functional significance | Triggers impulse conduction to next segment | Restores membrane for next impulse |
Key Points: Transmission of Nerve Impulse
- Nerve Impulse
A nerve impulse is a wave of bioelectrical (electrochemical) disturbance that travels along the neuron membrane. - Resting (Polarized) State
In a resting neuron, the membrane is polarized with excess Na⁺ outside and K⁺ inside, creating a resting potential of about –70 mV. - Sodium–Potassium Pump
Active transport of Na⁺ out and K⁺ into the neuron against their gradients using ATP energy is called the Na⁺/K⁺ exchange pump. - Role of Ion Channels
Voltage-gated Na⁺ and K⁺ channels regulate membrane permeability and enable change from resting potential to active potential during impulse conduction.
Important Questions [41]
- Which of the following is a chemical transmitter in synapse of neurons?
- Describe nervous system in planaria with well labelled diagram.
- Short answer question List the properties of the nerve fibres.
- Degeneration of dopamine producing neurons in the CNS causes ______ disease.
- Spinal cord and sympathetic ganglion of autonomous nervous system are connected by ______________.
- Describe T.S. of the spinal cord.
- Give the name and type of I, IV and VII cranial nerves.
- Write the names of any four motor cranial nerves with their appropriate serial number.
- Give reason – All spinal nerves are of mixed type.
- Differentiate between sympathetic and parasympathetic nervous system with reference to the following: Pre and post-ganglionic nerve fibres Effect on heartbeat
- Photoreceptor cells are present in
- Select and Write the Most Appropriate Answer from the Given. Which of the Following Hormones is Responsible for Regulating the Blood Sugar Level in the Human Body?
- State properties of hormones.
- Membrane bound receptors and hormones produce second messengers like _________.
- A person suffering from diabetes insipidus shows __________.
- Define the following term: Hormones
- State the Function of Relaxin.
- Enlist Human Endocrine Glands.
- Describe the T. S. of Thyroid Gland
- Add a Note on Deficiency of Thyroxine.
- _______ Maintains Basic Metabolic Rate.
- State the names of hormones and glands secreting them: Growth of thyroid gland.
- State the names of hormones and glands secreting them: Controls tubular absorption of water in the kidney.
- Draw a neat diagram of thyroid gland and label thyroid follicle, follicular cells and blood capillaries.
- A child has low BMR, delayed puberty and mental retardation. Identify the disease.
- Mention the difference between hypothyroidism and hyperthyroidism.
- Calcium and Phosphate ions are balanced between blood and other tissues by ______.
- Which endocrine gland plays an important, role in improving immunity?
- State the names of hormones and glands secreting them: Development of immune system and maturation of T-lymphocyte.
- Give the name of endocrine gland which is prominert at birth but gets gradually atrophied in adult stage.
- Name and describe hormones secreted by ovaries.
- The catecholamines are secreted by _________.
- State the names of hormones and glands secreting them: Stimulates liver and muscles for glycogenesis.
- Which cells of islets of Langerhans produce a hormone insulin?
- Which hormones stimulate liver for glycogenesis and glycogenolysis?
- Sketch and Label Formation of Typical Spinal Nerve.
- A Person is Showing Symptoms like Increased Bmr, Heart Rate, Pulse Rate, Blood Pressure and Deposition of
- Explain the mechanism of reflex action with the help of a suitable diagram.
- What is a reflex action?
- Give examples of unconditional reflexes
- Sketch and label reflex arc
Concepts [34]
- Control and Co-ordination
- Nervous System in Hydra
- Nervous System in Planaria (Flatworm)
- Neural Tissue
- Neuron (Or Nerve Cell)
- Neuroglial Cells (Or Glial Cells)
- Human Nervous System
- Central Nervous System (CNS)
- The Human Brain
- The Spinal Cord
- Peripheral Nervous System > Somatic Nervous System
- Sensory Receptors
- The Human Eye
- Human Ear
- Disorders of Nervous System
- Chemical Coordination
- Human Endocrine System
- The Hypothalamus
- Pituitary Gland or Hypophysis Gland
- The Pineal Gland
- Thyroid Gland
- Parathyroid Gland
- Thymus Gland
- Adrenal Gland (Suprarenal Gland)
- Pancreas (Islets of Langerhans)
- Reproductive Glands (Gonads)
- Synapse
- Types of Synapse
- Transmission of Nerve Impulse
- Generation of nerve impulse
- Reflex Action
- Peripheral Nervous System > Autonomic Nervous System
- Diffuse Endocrine Glands
- Overview of Control and Co-ordination
