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Revision: Control and Co-ordination Biology HSC Science (General) 12th Standard Board Exam Maharashtra State Board

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Definitions [37]

Definition: Response

A response is the reaction or change in an organism produced as a result of a stimulus.

Definition: Stimulus

A stimulus is any sudden change in the internal or external environment that brings about a response in an organism.

Definition: Neuron (Nerve Cell)

A neuron is a specialised cell that forms the structural and functional unit of the nervous system and is responsible for transmitting nerve impulses.

Definition: Effectors

Effectors are muscles or glands that produce a response by contracting or secreting substances when stimulated by nerve impulses.

Define the following term:

Synaptic cleft

Axon terminals are closely placed near the dendrites of another one or more neurons but are not connected. Such gaps in between are called synaptic clefts.

Definition: Receptors

Receptors are specialised sensory cells that receive stimuli and convert them into nerve impulses.

Definition: Nerve Impulse

A nerve impulse is an electrical disturbance that travels along a neuron in response to a stimulus.

Definition: Synaptic Cleft

Axon terminals are closely placed near the dendrites of another one or more neurons but are not connected. Such gaps in between are called synaptic clefts.

Define the following term:

Nerve

A nerve is a bundle of axons from numerous neurons encased in a protective sheath.

Definition: Nodes of Ranvier

Nodes of Ranvier are gaps present at intervals in the myelin sheath that help in faster transmission of nerve impulses.

Definition: Neurolemma (Neurilemma)

Neurolemma is the outermost thin protective sheath covering the myelin sheath of a nerve fibre.

Define the following: 

Neuron  

Neurons are the building blocks of the nervous system and transmit information throughout the body.

Define the following:

Reflex arc

The path that an impulse takes in a reflex action is called a reflex arc.

Define the following: 

Motor neuron:   

The neurons which carry impulses from the brain or spinal cord to the body parts are called motor or efferent neurons.

Define the term:

Sensory neuron

The neurons which carry impulses from the body parts to the spinal cord or the brain are called sensory or afferent neurons. For example, the optic nerve of the eye.

Define stimulus.

A stimulus is an agent or a sudden change in the external or internal environment that changes an organism or body parts. e.g., light, sound, heat, pain, hunger.

Definition: Meninges

The brain is protected by 3 membranous coverings called meninges (meninx: membrane) which continue backwards on the spinal cord.

Definition: Meningitis

Inflammation of the meninges is called meningitis.

Define the following term:

Adaptation

Adaptation is the process by which the human eye adjusts to changes in light intensity.

  1. Light Adaptation: When a person moves from a dark environment to a brightly lit area (e.g., stepping out of a cinema hall in the afternoon), they initially experience a dazzling effect. After a few seconds, the eyes adjust to the brightness. This process is called light adaptation.
  2. Dark Adaptation: When a person enters a dark area from a brightly lit environment (e.g., entering a cinema hall), they initially struggle to see clearly. Gradually, their vision improves as the eyes adapt to the darkness. This process is called dark adaptation.

Define the following term:

Ear ossicles

The middle ear contains three tiny bones malleus, incus and stapes or hammer, anvil and stirrup in popular terms and a eustachian tube which connects the cavity of the middle ear with the throat. The three bones are collectively called the ear ossicles ( osseus: bone, ossicle : little bone).

Define the following term:

Hormones

Hormones are chemical messengers created by the endocrine glands and transported through the bloodstream to govern body functions such as development, metabolism, reproduction and mood by interacting with specific target cells.

Definition: Endocrine System

A group of glands and glandular cells that secrete hormones to regulate and coordinate various functions in the body through chemical control.

Define the following term:

Endocrine system

The endocrine system is defined as a group of organs performing an overall common function. The endocrine glands secrete certain chemicals called hormones.

Define the following:

Hormone

Hormone is a molecule that is created and secreted in very minute quantities into the blood stream by an endocrine gland or a specialized nerve cell that governs the growth or functioning of a specific tissue organ in a distant area of the body, e.g., insulin

Define the following term:

Myxoedema

Myxoedema is a condition that affects an adult if his thyroid does not function properly; in this condition, the person becomes sluggish with swelling of the face and hands.

Define the following:

Mineralization

It is the process by which some microbes decompose humus to release inorganic nutrients.

Definition: Islets of Langerhans

The special groups of hormone-secreting cells scattered in the pancreas that produce insulin, glucagon, and other hormones for blood sugar regulation are called Islets of Langerhans.

Define the following:

Exocrine gland

  • Glands that discharge secretions into ducts are known as exocrine glands.
  • Sebaceous glands in the skin, salivary glands in the buccal cavity, etc. are examples of exocrine glands.
Definition: Synapse

Synapse (syn: together, apse: gap/window) is the point of contact between the terminal branches of the axon of a neuron with the dendrites of another neuron separated by a fine gap.

or

The junction between two nerve cells having a minute gap called synaptic cleft through which nerve impulse is transmitted by neurotransmitters is called synapse.

Definition: Sodium Pump

The sodium pump is a cellular mechanism that uses energy from ATP to actively transport sodium ions out of the axon, helping restore the resting state after depolarisation.

Definition: Polarised State

The polarised state is when the outer side of a nerve fibre carries a positive charge due to more Na⁺ ions outside the axon membrane in the resting condition.

Definition: Reflex Action

It is an automatic/quick/immediate, involuntary action in the body brought about by a stimulus.

Define the following:

Reflex action

Reflex action is an automatic/quick/immediate, involuntary action in the body brought about by a stimulus. This mechanism prevents injury to the body by triggering a rapid and automatic response.

Definition: Synaptic Cleft

The small intercellular space of about 20–30 nm present between presynaptic and postsynaptic neurons is called synaptic cleft.

Definition: Synaptic Transmission

The process by which a nerve impulse is conducted from the presynaptic neuron to the postsynaptic neuron by neurotransmitters is called synaptic transmission.

Definition: Electrical Synapse

The type of synapse in which transmission of impulse occurs directly through a narrow gap by electrical current is called electrical synapse.

Definition: Chemical Synapse

The type of synapse in which transmission of impulse occurs through chemical neurotransmitters across a wider synaptic gap is called chemical synapse.

Key Points

Key Points: Neuron
  1. The neuron has three main parts: cell body (cyton), dendrites, and axon.
  2. The cell body contains the nucleus and cytoplasm, but lacks a centrosome, so it cannot divide.
  3. Dendrites are branched projections that receive and conduct impulses toward the cell body.
  4. Axon is a long extension that transmits impulses away from the cell body; it is often covered with a myelin sheath interrupted by Nodes of Ranvier.
  5. The axon ends in terminal bulbs that release neurotransmitters across a synaptic cleft to the next neuron's dendrite.
Key Points: Human Nervous System
  1. Receptors in sense organs detect changes in the environment and send signals to the brain through neurons.
  2. A neuron consists of dendrites, cell body, and axon, which help in receiving and transmitting electrical impulses.
  3. The electrical impulse travels from the dendrite to the axon terminal and then is passed to the next neuron or target cell.
  4. At the synapse, special chemicals help transmit the impulse to another neuron or to a muscle or gland.
  5. A neuromuscular junction allows the nerve impulse to reach a muscle fibre, causing it to contract and respond.
 
Key Points: Different regions of Brain and its functions:
Part Description Location Structure Main Functions
Cerebrum Largest part of the brain, also called the large brain Upper part of cranial cavity Two hemispheres with many convolutions Voluntary actions; intelligence, memory, thinking, decision-making
Cerebellum Smaller part of brain situated below cerebrum Back of cranial cavity Shallow grooves on surface Coordination of movements; body balance
Medulla Oblongata Hindmost part of brain connecting brain to spinal cord Lower brainstem Pyramidal structures; continuous with spinal cord Controls breathing, heartbeat, swallowing, coughing
Spinal Cord Long cylindrical part of CNS extending from medulla Vertebral column Ends as filum terminale Reflex actions; conduction of impulses to and from brain
Key Points: Human Brain
  1. The human brain is the largest in proportion to body size among all animals and is protected inside the cranium.
  2. The adult brain weighs about 1.35 kg, makes up about 2% of body weight, and is 80% water.
  3. The brain uses more than 25% of the total oxygen taken into the body.
  4. It is covered by three protective membranes called meninges: dura mater, arachnoid, and pia mater.
  5. The space between the meninges contains cerebrospinal fluid (CSF), which cushions the brain and also fills the brain’s ventricles and the spinal cord canal.
Key Points: Spinal Cord
  1. The spinal cord extends from the medulla to the second lumbar vertebra, enclosed in the vertebral column.
  2. Gray matter is internal, and white matter is external, opposite to the brain’s structure.
  3. A central canal filled with cerebrospinal fluid runs through it, aiding in shock absorption and nutrient exchange.
  4. It is enclosed by the same meninges as the brain: dura mater, arachnoid, and pia mater.
  5. Functions include reflex actions below the neck, and transmission of sensory and motor signals between the brain and body.
Key Points: Types of PNS
Type Cranial Nerves Spinal Nerves
Origin Directly from the brain. From the spinal cord.
Function Connect the brain to the head, neck, thorax, and abdomen; manage motor control, sensory perception, and digestion. Link the spinal cord to limbs, skin, and other body parts; transmit sensory information and motor commands.
Number 12 pairs 31 pairs
Region Head, thorax, abdomen Various spinal regions

Examples/

Details

Optic nerve (2): Vision.
Vagus nerve (10): heart rate, digestion, and breathing.
Cervical (8 pairs): neck, shoulders, arms.
Thoracic (12 pairs): chest, abdominal muscles.
Lumbar/Sacral (10 pairs): legs, pelvis, lower back.
Coccygeal (1 pair): Tailbone.
Key Points: Human Eye
  • The human eye works like a camera, forming a real and inverted image on the retina, which is light-sensitive.
  • The cornea allows light to enter the eye and performs most of the refraction, while the lens fine‑tunes the focus.
  • The iris controls the pupil, regulating the amount of light entering the eye—contracting in bright light and widening in dim light.
  • The power of accommodation is the ability of the eye lens to change its focal length by altering its curvature using the ciliary muscles.
  • For a normal eye, the near point is 25 cm and the far point is at infinity.
Key Points: Human Ear
  1. The ear has three main parts: outer ear, middle ear, and inner ear.
  2. The outer ear includes the pinna and auditory canal, ending at the eardrum (tympanum).
  3. The middle ear contains three tiny bones — malleus (hammer), incus (anvil), and stapes (stirrup) — called ossicles, and is connected to the throat by the eustachian tube.
  4. The stirrup fits on the oval window, and a second membrane-covered opening called the round window separates the middle ear from the inner ear.
  5. The inner ear includes the cochlea (with the organ of Corti for hearing) and the semicircular canals for dynamic balance.
  6. The vestibule (utriculus and sacculus) contains sensory cells responsible for static balance when the body is stationary.
Key Points: Pituitary Gland

1. The pituitary gland, also known as the master gland, is a pea-sized endocrine gland located below the hypothalamus and consists of anterior and posterior lobes.

2. The anterior pituitary secretes:

  • Growth hormone (GH): controls body growth; deficiency causes dwarfism, excess causes gigantism or acromegaly.
  • TSH: stimulates the thyroid.
  • ACTH: regulates adrenal cortex.
  • Gonadotropic hormones: control testes and ovaries.

3. The posterior pituitary secretes:

  • ADH (vasopressin): controls water reabsorption in kidneys; deficiency causes diabetes insipidus.
  • Oxytocin: triggers uterine contractions during childbirth and helps in milk ejection.

4. Tropic hormones are those that stimulate other endocrine glands to release their hormones.

5. Disorders from hormonal imbalance include gigantism, acromegaly, and diabetes insipidus.

Key Points: Thyroid Gland

1. The thyroid gland is a butterfly-shaped gland located in the neck and secretes thyroxine and calcitonin.

2. Thyroxine controls basal metabolic rate, influences growth, mental development, bone formation, and body temperature.

3. Hypothyroidism may cause:

  • Simple goitre (due to iodine deficiency),
  • Cretinism (dwarfism and mental retardation in children),
  • Myxoedema (sluggishness and swelling in adults).

4. Hyperthyroidism leads to exophthalmic goitre with symptoms like protruding eyes, neck swelling, high metabolism, rapid heartbeat, and breathlessness.

5. Use of iodised salt helps prevent thyroid-related issues caused by iodine deficiency.

Key Points: Adrenal Glands
  1. The adrenal glands are located above each kidney and consist of two parts: the medulla (inner) and the cortex (outer).
  2. The adrenal medulla secretes adrenaline, the "emergency hormone," which increases heartbeat, blood pressure, and blood glucose during stress.
  3. The adrenal cortex produces cortisone, mineralocorticoids, glucocorticoids, and sex corticoids, which regulate metabolism, stress response, and salt-water balance.
  4. Hyposecretion of cortisone causes Addison’s disease, while hypersecretion causes Cushing’s syndrome.
  5. Hormonal imbalance from adrenal cortex overgrowth can cause adrenal virilism in women (male traits) and feminization in men (e.g., breast enlargement).
Key Points: Pancreas
  1. Pancreas functions both as an exocrine gland (secreting pancreatic juice into the duodenum) and an endocrine gland (secreting hormones into the blood).
  2. The Islets of Langerhans contain beta cells (secrete insulin) and alpha cells (secrete glucagon), which regulate blood sugar levels.
  3. Insulin lowers blood glucose by promoting glucose uptake by cells and storing excess glucose as glycogen in the liver and muscles.
  4. Under-secretion of insulin causes diabetes mellitus (hyperglycemia), with symptoms like excessive urination, thirst, weakness, and sugar in urine.
  5. Glucagon raises blood sugar by converting glycogen to glucose in the liver; overdose of insulin can lead to hypoglycemia or insulin shock.
Key Points: Reflex Action
  1. Voluntary actions are performed consciously, while involuntary actions (reflexes) occur automatically without conscious control.
  2. A stimulus is any change in the environment that initiates a reflex action.
  3. Reflex actions are quick, automatic responses to stimuli and do not require conscious thought.
  4. Examples of reflexes include withdrawal of hand from a hot object, shivering in cold, and sweating in heat.
  5. All reflexes are triggered by sensory stimulation and result in either muscular movement or glandular secretion.
Key Points: Disorders of nervous system
Disorder Cause Major Symptoms Key Points
Psychological Disorders Disturbance in mood, thinking, or behaviour Anxiety, depression, stress, poor attention, abnormal behaviour Includes ID, ASD, BD, depression, anxiety, ADHD; affects daily life
Parkinson’s Disease Degeneration of dopamine-producing neurons in CNS Tremors, muscle stiffness, difficulty in walking, poor coordination Symptoms develop gradually; movement disorder
Alzheimer’s Disease Loss of cholinergic neurons and amyloid protein accumulation Memory loss, impaired thinking, reasoning, and behaviour Most common dementia; age-related; no cure but progression can be slowed
Key Points: Generation of nerve impulse
Aspect Depolarization Repolarization
Meaning Change in membrane polarity from resting to active state Restoration of membrane polarity to resting state
Na⁺ channel status Voltage-gated Na⁺ channels open Na⁺ channels close and become inactive
K⁺ channel status K⁺ channels remain closed Voltage-gated K⁺ channels open
Ion movement Rapid influx of Na⁺ into the axon Rapid efflux of K⁺ out of the axon
Membrane potential Rises from –70 mV to +30 to +60 mV Falls back towards –70 mV
Electrical charge Inner surface becomes positive Inner surface becomes negative
Nature of process Initiates action potential Terminates action potential
Functional significance Triggers impulse conduction to next segment Restores membrane for next impulse
Key Points: Transmission of Nerve Impulse
  1. Nerve Impulse
    A nerve impulse is a wave of bioelectrical (electrochemical) disturbance that travels along the neuron membrane.
  2. Resting (Polarized) State
    In a resting neuron, the membrane is polarized with excess Na⁺ outside and K⁺ inside, creating a resting potential of about –70 mV.
  3. Sodium–Potassium Pump
    Active transport of Na⁺ out and K⁺ into the neuron against their gradients using ATP energy is called the Na⁺/K⁺ exchange pump.
  4. Role of Ion Channels
    Voltage-gated Na⁺ and K⁺ channels regulate membrane permeability and enable change from resting potential to active potential during impulse conduction.

Important Questions [41]

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