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Karnataka Board PUCPUC Science Class 11

How Does Pepsinogen Change into Its Active Form

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Question

How does pepsinogen change into its active form?

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Solution 1

Pepsinogen is a precursor of pepsin stored in the stomach walls. It is converted into pepsin by hydrochloric acid. Pepsin is the activated in the form of pepsinogen.

Pepsinogen  Pepsin + Inactive peptide

(Inactive) (Active)

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Solution 2

The proenzyme pepsinogen, on exposure to hydrochloric acid, secreted by oxyntic cells of gastric glands gets converted into the active enzyme pepsin, the proteolytic enzyme of the stomach.

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