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Question
Differentiate between the following:
mRNA and tRNA
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Solution
| Sr. No. | mRNA | tRNA |
| 1. | It accounts for around 5% of total RNA in the cell. | It contributes to around 15% of the total RNA in the cell. |
| 2. | It consists of 75-6000 bases. | It consists of between 73-93 bases. |
| 3. | Its molecular weight ranges from 25000 to 2000000 daltons. | Its molecular weight is about 25000 daltons. |
| 4. | The sedimentation coefficient is 6-30S. | Its sedimentation coefficient is 4S. |
| 5. | It is the longest RNA with the highest molecular weight but the least abundant. | It is the smallest RNA and is coiled like a cloverleaf. |
| 6. | It contains the codes that create proteins. | It carries code that is complementary to the RNA code. |
| 7. | It is synthesised by RNA polymerase II in the nucleus. | It is synthesised in the nucleus by RNA polymerase III. |
| 8. | There are no base modifications in the coding region. | Approximately 5% of the bases are changed. |
| 9. | It is classified into numerous categories based on the number of genes. | There are approximately 100 types. |
| 10. | It is short-lived (3 seconds to a few days) and typically degrades following protein synthesis. | It is quite stable, may be used repeatedly, and degrades slowly. |
| 11. | It is known as template/nuclear/messenger or informative RNA because it transports genetic information provided by DNA. | Soluble or adaptor RNA transports amino acids to mRNA during protein synthesis. |
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