Question

Differentiate between the following:

mRNA and tRNA

Answer 1

Sr. No.	mRNA	tRNA
1.	It accounts for around 5% of total RNA in the cell.	It contributes to around 15% of the total RNA in the cell.
2.	It consists of 75-6000 bases.	It consists of between 73-93 bases.
3.	Its molecular weight ranges from 25000 to 2000000 daltons.	Its molecular weight is about 25000 daltons.
4.	The sedimentation coefficient is 6-30S.	Its sedimentation coefficient is 4S.
5.	It is the longest RNA with the highest molecular weight but the least abundant.	It is the smallest RNA and is coiled like a cloverleaf.
6.	It contains the codes that create proteins.	It carries code that is complementary to the RNA code.
7.	It is synthesised by RNA polymerase II in the nucleus.	It is synthesised in the nucleus by RNA polymerase III.
8.	There are no base modifications in the coding region.	Approximately 5% of the bases are changed.
9.	It is classified into numerous categories based on the number of genes.	There are approximately 100 types.
10.	It is short-lived (3 seconds to a few days) and typically degrades following protein synthesis.	It is quite stable, may be used repeatedly, and degrades slowly.
11.	It is known as template/nuclear/messenger or informative RNA because it transports genetic information provided by DNA.	Soluble or adaptor RNA transports amino acids to mRNA during protein synthesis.