Question

Assertion (A): Phenylketonuria is a recessive hereditary disorder which leads to accumulation of phenyl pyruvic acid and other derivatives in the brain.

Reason (R): The affected individual lacks an enzyme that converts amino acid phenylalanine into tyrosine.

Options

• Both assertion (A) and reason (R) are true, and reason is the correct explanation of assertion.

• Both assertion (A) and reason (R) are true, but reason is not the correct explanation of assertion.

• Assertion (A) is true but reason (R) is false.

• Both assertion (A) and reason (R) are false.

Answer 1

Both assertion (A) and reason (R) are true, and reason is the correct explanation of assertion.

Explanation:

Both statements are true. Lack of phenylalanine hydroxylase prevents the normal conversion of phenylalanine to tyrosine, leading to accumulation of phenylalanine and phenylpyruvic acid; the disorder is recessive.