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Question
Assertion (A): Sickle cell anaemia is an autosome linked genetically inherited disorder affecting many new born babies.
Reason (R): It is caused by substitution of valine by glutamic acid at the sixth position of the beta globin chain of haemoglobin molecule.
Options
Both assertion (A) and reason (R) are true, and reason is the correct explanation of assertion.
Both assertion (A) and reason (R) are true, but reason is not the correct explanation of assertion.
Assertion (A) is true but reason (R) is false.
Both assertion (A) and reason (R) are false.
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Solution
Assertion (A) is true but reason (R) is false.
Explanation:
Sickle cell anaemia is an autosomal inherited disorder, so the assertion is true. The reason reverses the amino-acid substitution: glutamic acid is replaced by valine at the sixth position.
