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प्रश्न
What is a recombinant DNA vaccine? Give two examples.
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उत्तर
Recombinant DNA vaccines are the vaccines which are manufactured by Recombinant DNA technology. It involves the construction of a plasmid using a copy of DNA from pathogen with an empty plasmid.
Examples:
- Hepatitis B is produced from yeast culture (Saccharomyces cerevisiae).
- Japanese encephalitis vaccine.
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संबंधित प्रश्न
Suggest any two possible treatments that can be given to a patient exhibiting adenosine deaminase deficiency.
Recombination DNA−technology is of great importance in the field of medicine. With the help of a flow chart, show how this technology has been used in preparing genetically engineered human insulins.
State the cause of ADA deficiency in humans.Mention a possible cure for an ADA deficiency patient.
Give a schematic representation of the transformation of a pro-insulin into insulin.
Write any two biochemical/molecular diagonostic procedures for early detection of viral infection. Explain the principle of any one of them.
Answer the following question.
Explain the various steps involved in the production of artificial insulin.
If a person thinks he is infected with HIV, due to unprotected sex, and goes for a blood test. Do you think a test such as ELISA will help? If so why? If not, why?
Explain how ADA deficiency can be corrected?
What are recombinant vaccines? Explain the types.
A patient suffering from diabetes mellitus will have ______.
The hormone insulin is secreted by:
C-peptide of human insulin is ______.
A probe which is a molecule used to locale-specific sequences in a mixture of DNA or RNA Mole cubs could be ______.
Now a days it is possible to detect the mutated gene causing cancer by allowing a radioactive probe to hybridize its complimentary DNA in a clone of cells, followed by its detection using autoradiography because ______
With regard to insulin choose the correct options.
- C-peptide is not present in mature insulin.
- The insulin produced by rDNA technology has C-peptide.
- The pro-insulin has C-peptide.
- A-peptide and B-peptide of insulin are interconnected by disulphide bridges.
Choose the correct answer from the options given below.
Discuss briefly how a probe is used in molecular diagnostics.
How is a mature, functional insulin hormone different from its prohormone form?
A host cell must be made competent, before it is able to receive an rDNA. Justify.
- Assertion: PCR is a powerful technique to identify genetic disorders.
- Reason: PCR can detect mutations in low amounts of DNA.
Illustrate using any one example of transgenic bacteria.
